KIT and LYN

  • Number of citations of the paper that reports this interaction (PMID 9341198)
  • 27
  • Data Source:
  • HPRD (in vivo, in vitro)

KIT

LYN

Gene Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog LYN proto-oncogene, Src family tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B TEC YES1 115 interactors: ACTB ADAM15 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CREBBP CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IL1B IL2RB IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT LCP2 LIME1 MAP4K1 MAPK3 MATK MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NMT1 NPHS1 PAG1 PAK2 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SPHK1 SPHK2 SRC STAT3 SYK TEC TNF TRAT1 TRIM28 TRIP10 TRPV4 TYK2 UBB UHRF2 UNC119
Entrez ID 3815 4067
HPRD ID 01287 01301
Ensembl ID ENSG00000157404 ENSG00000254087
Uniprot IDs P10721 A8K379 P07948 Q6NUK7
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2VIF 3G0E 3G0F 4HVS 1W1F 1WA7 3A4O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
5r  abrogated  amino  betac  binding  blocked  coupled  created  csf  exact  finding  granulocyte  help  involves  macrophage  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
Tagcloud (Difference) ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  cytokines  immunomagnetic  leukemic  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
5r  abrogated  amino  betac  binding  blocked  coupled  created  exact  finding  help  involves  map  modules  narrowed  nine  overlapping  permeable  physically  proline  proximal  residues  sequential  site  stearation  unstimulated 
Tagcloud (Intersection) ?
csf  granulocyte  macrophage