SEC22A and SYNE4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SEC22A	SYNE4
Gene Name		SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	spectrin repeat containing, nuclear envelope family member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane SNARE Complex	Integral Component Of Nuclear Outer Membrane LINC Complex
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity
	Biological Process	Exocytosis ER To Golgi Vesicle-mediated Transport Protein Transport Vesicle Fusion With Golgi Apparatus	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: DTX2 EDA ERLIN1 FATE1 MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79	52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		26984	163183
HPRD ID		15313	08776
Ensembl ID			ENSG00000181392
Uniprot IDs		Q96IW7	Q8N205
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-associated Ubiquitin-dependent Protein Catabolic Process Hair Follicle Development Hair Cycle Process Hair Cycle Positive Regulation Of Eosinophil Degranulation Cuticle Development ER-associated Misfolded Protein Catabolic Process Cornification Trachea Gland Development Establishment Of Epithelial Cell Apical/basal Polarity Salivary Gland Cavitation Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Skin Development Positive Regulation Of Immunoglobulin Secretion Establishment Of Monopolar Cell Polarity SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Synaptic Vesicle Fusion To Presynaptic Membrane Epidermis Development Cellular Response To Nitric Oxide Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Immunoglobulin Secretion Regulation Of Autophagic Vacuole Assembly Response To Misfolded Protein Response To Nitric Oxide Epithelium Development Positive Regulation Of Protein Transport Positive Regulation Of Cholesterol Storage Establishment Of Skin Barrier Establishment Of Epithelial Cell Polarity Exocytosis Hair Follicle Placode Formation Regulation Of Vacuole Organization Lipoprotein Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Epithelial Cell Maturation Positive Regulation Of NF-kappaB Import Into Nucleus	ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction
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