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SYNE4 and CLEC7A
Number of citations of the paper that reports this interaction (PubMedID
21516116
)
20
Data Source:
BioGRID
(two hybrid)
SYNE4
CLEC7A
Description
spectrin repeat containing nuclear envelope family member 4
C-type lectin domain containing 7A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Nuclear Outer Membrane
Membrane
Meiotic Nuclear Membrane Microtubule Tethering Complex
Cytoplasm
Plasma Membrane
Cell Surface
Membrane
Molecular Function
Protein Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Establishment Of Epithelial Cell Apical/basal Polarity
Cell Activation
Response To Yeast
Detection Of Yeast
Stimulatory C-type Lectin Receptor Signaling Pathway
Immune System Process
Positive Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Cell Surface Pattern Recognition Receptor Signaling Pathway
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-23 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of MAPK Cascade
Innate Immune Response
Leukocyte Activation
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Phagocytosis
Positive Regulation Of Calcium-mediated Signaling
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Respiratory Burst
Antifungal Innate Immune Response
Regulation Of Calcineurin-NFAT Signaling Cascade
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Apoptotic Signaling Pathway
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Positive Regulation Of T-helper 17 Type Immune Response
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Interacting Genes
56 interacting genes:
ABT1
ADIPOQ
BRICD5
C3orf52
CD47
CEP19
CFTR
CLDN19
CLDN7
CLDN8
CLEC7A
CMTM5
CSNK2B
CXCL9
DEFB121
ECE2
EDDM3B
EMP1
ENTPD3
FAM241B
FATE1
GADD45A
GSK3B
IGFBP5
ITM2B
KLHL12
KLRG1
KTN1
MALL
MARCHF2
NAGK
OCLN
OLFM4
OSTCP1
PAQR5
PLPP6
RIPPLY2
RPS6KA6
SEC22A
SEC23B
SENP2
SFTPC
SLN
SMCO4
TCEA2
TMEM115
TMEM140
TMEM147
TMEM182
TMEM248
TMPRSS4
TRIM69
TSPAN15
VTI1B
ZNF250
ZNF648
48 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CFTR
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
163183
64581
HPRD ID
08776
08396
Ensembl ID
ENSG00000181392
ENSG00000172243
Uniprot IDs
Q8N205
A0A0S2Z5Q1
A0A2Z5YRT6
A0A2Z5YRU4
Q68D78
Q9BXN2
PDB IDs
6R16
6WMD
Enriched GO Terms of Interacting Partners
?
Protein Binding
Bicellular Tight Junction Assembly
Tight Junction Organization
Tight Junction Assembly
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Apicolateral Plasma Membrane
Regulation Of Glycogen (starch) Synthase Activity
Membrane
Plasma Membrane
Positive Regulation Of Viral Entry Into Host Cell
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Viral Life Cycle
Protein Binding
Mitochondrial Outer Membrane Permeabilization
Mitochondrial Protein Catabolic Process
Cytokine Receptor Activity
External Side Of Plasma Membrane
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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