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SYNE4 and GADD45A
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SYNE4
GADD45A
Gene Name
spectrin repeat containing, nuclear envelope family member 4
growth arrest and DNA-damage-inducible, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Nuclear Outer Membrane
LINC Complex
Nucleus
Cytoplasm
Molecular Function
Core Promoter Binding
Protein Binding
Biological Process
Establishment Of Epithelial Cell Apical/basal Polarity
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Activation Of MAPKKK Activity
DNA Repair
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Cell Cycle Arrest
Centrosome Cycle
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
52 interactors:
ABT1
ADIPOQ
BRICD5
C10orf35
C3orf52
CD47
CEP19
CLDN7
CLDN8
CLEC7A
CMTM5
CSGALNACT2
CSNK2B
CXCL9
DEFB121
ECE2
EDDM3B
EMP1
ENTPD3
FATE1
GADD45A
GSK3B
ITM2B
KLC4
KLHL12
KLRG1
KTN1
MALL
MARCH2
NAGK
OCLN
OLFM4
OSTCP1
PAQR5
RIPPLY2
RPS6KA6
SEC22A
SEC23B
SENP2
SFTPC
SLN
SMCO4
TMEM115
TMEM140
TMEM147
TMEM182
TMEM248
TMPRSS4
TRIM69
TSPAN15
VTI1B
ZNF250
65 interactors:
ADAP1
ASCC2
AURKA
BAG6
C14orf1
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
DCTN2
DNAJC13
EEF1A1
EEF1G
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
HIST1H1A
HIST1H2AL
HIST2H2BE
HIST3H3
HIST4H4
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
Entrez ID
163183
1647
HPRD ID
08776
00528
Ensembl ID
ENSG00000181392
ENSG00000116717
Uniprot IDs
Q8N205
A5JUZ3
P24522
PDB IDs
2KG4
Enriched GO Terms of Interacting Partners
?
ER To Golgi Vesicle-mediated Transport
Negative Regulation Of Binding
Regulation Of Binding
Golgi Vesicle Transport
Adiponectin-activated Signaling Pathway
Vesicle Fusion With Golgi Apparatus
Negative Regulation Of Protein Binding
Response To External Stimulus
Regulation Of Glycogen (starch) Synthase Activity
Cellular Response To Mechanical Stimulus
Vesicle-mediated Transport
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Metabolic Process
Cell Cycle
Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cellular Response To Organic Substance
Regulation Of Protein Metabolic Process
Organelle Organization
DNA Packaging
DNA Conformation Change
Negative Regulation Of Cellular Metabolic Process
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromosome Organization
Cell Aging
Protein Complex Assembly
Chromatin Organization
Negative Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Cell Death
Death
Positive Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Chromatin Assembly Or Disassembly
Stress-induced Premature Senescence
Immune Response
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Mitotic DNA Damage Checkpoint
Immune System Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Innate Immune Response
Mitotic DNA Integrity Checkpoint
Response To Toxic Substance
Positive Regulation Of Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Oxygen Levels
Tagcloud
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?