SEC22A and DTX2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SEC22A	DTX2
Gene Name		SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	deltex 2, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane SNARE Complex	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Exocytosis ER To Golgi Vesicle-mediated Transport Protein Transport Vesicle Fusion With Golgi Apparatus	Notch Signaling Pathway Protein Ubiquitination
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: DTX2 EDA ERLIN1 FATE1 MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79	41 interactors: ABHD16A ALKBH4 ARNT2 C1orf94 DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS RBPMS RFX6 RHOXF2 RIMBP3 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1
Entrez ID		26984	113878
HPRD ID		15313	16841
Ensembl ID			ENSG00000091073
Uniprot IDs		Q96IW7	Q86UW9
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-associated Ubiquitin-dependent Protein Catabolic Process Hair Follicle Development Hair Cycle Process Hair Cycle Positive Regulation Of Eosinophil Degranulation Cuticle Development ER-associated Misfolded Protein Catabolic Process Cornification Trachea Gland Development Establishment Of Epithelial Cell Apical/basal Polarity Salivary Gland Cavitation Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Skin Development Positive Regulation Of Immunoglobulin Secretion Establishment Of Monopolar Cell Polarity SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Synaptic Vesicle Fusion To Presynaptic Membrane Epidermis Development Cellular Response To Nitric Oxide Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Immunoglobulin Secretion Regulation Of Autophagic Vacuole Assembly Response To Misfolded Protein Response To Nitric Oxide Epithelium Development Positive Regulation Of Protein Transport Positive Regulation Of Cholesterol Storage Establishment Of Skin Barrier Establishment Of Epithelial Cell Polarity Exocytosis Hair Follicle Placode Formation Regulation Of Vacuole Organization Lipoprotein Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Epithelial Cell Maturation Positive Regulation Of NF-kappaB Import Into Nucleus	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Transcription From RNA Polymerase II Promoter Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Innate Immune Response Protein K11-linked Ubiquitination RNA Metabolic Process Cellular Response To Oxygen Levels Heart Trabecula Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Hypoxia Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Pancreatic Epsilon Cell Differentiation Glutaminyl-tRNA Aminoacylation Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Pancreatic D Cell Differentiation Cleavage Furrow Ingression Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Glandular Epithelial Cell Differentiation Signal Transduction Trabecula Morphogenesis Positive Regulation Of Innate Immune Response Vesicle Fusion Regulation Of Immune System Process Prolyl-tRNA Aminoacylation Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Histamine Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?