SYNE4 and CXCL9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYNE4	CXCL9
Gene Name		spectrin repeat containing, nuclear envelope family member 4	chemokine (C-X-C motif) ligand 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane LINC Complex	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function		Cytokine Activity Protein Binding Chemokine Activity CXCR3 Chemokine Receptor Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of CAMP Metabolic Process Response To Lipopolysaccharide Regulation Of Cell Proliferation Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Chemokine-mediated Signaling Pathway Positive Regulation Of Myoblast Fusion
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	9 interactors: BMF CCDC155 CCR3 CXCR3 DPP4 PAX8 PTPN5 SFTPC SYNE4
Entrez ID		163183	4283
HPRD ID		08776	03416
Ensembl ID		ENSG00000181392	ENSG00000138755
Uniprot IDs		Q8N205	Q07325
PDB IDs
Enriched GO Terms of Interacting Partners?		ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction	Chemokine-mediated Signaling Pathway Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Thyroid-stimulating Hormone Secretion Regulation Of Endothelial Cell Proliferation Pronephric Field Specification Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Chemokine (C-C Motif) Ligand 11 Production Positive Regulation Of Angiogenesis Positive Regulation Of Thyroid Hormone Generation Kidney Rudiment Formation Thyroid-stimulating Hormone Signaling Pathway Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Cytosolic Calcium Ion Concentration Metanephric Comma-shaped Body Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Response To Cytokine Cytosolic Calcium Ion Homeostasis Metanephric Tubule Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Metanephric S-shaped Body Morphogenesis Regulation Of Thyroid Hormone Generation Comma-shaped Body Morphogenesis Anoikis Establishment Of Apical/basal Cell Polarity Metanephric Distal Convoluted Tubule Development Metanephric Nephron Tubule Morphogenesis Polarized Epithelial Cell Differentiation Positive Regulation Of Cell Proliferation Regulation Of Angiogenesis Pronephros Development Negative Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Protein Homooligomerization S-shaped Body Morphogenesis Positive Regulation Of Intracellular Transport T Cell Chemotaxis Metanephric Distal Tubule Development Regulation Of Cell-cell Adhesion Mediated By Integrin Chemokine Production Establishment Of Monopolar Cell Polarity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Tagcloud ?			academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Difference) ?			academic assessing auc bacilli centre chemoattractant cxcl10 cxcl11 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Intersection) ?