SYNE4 and SFTPC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYNE4	SFTPC
Gene Name		spectrin repeat containing, nuclear envelope family member 4	surfactant protein C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane LINC Complex	Extracellular Space Multivesicular Body Alveolar Lamellar Body
	Molecular Function		Protein Binding Protein Homodimerization Activity
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Respiratory Gaseous Exchange Circadian Rhythm Response To Glucose Response To Lipopolysaccharide Response To Retinoic Acid Response To Vitamin A Protein Homooligomerization Response To Glucocorticoid Response To CAMP Response To Hyperoxia Response To Interleukin-6 Response To Growth Factor Cellular Response To Mechanical Stimulus Cellular Response To Nitric Oxide
Pathways
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	9 interactors: CXCL9 NEDD4 PQBP1 SEC22A SEC61G SYNE4 TMEM79 WWP1 WWP2
Entrez ID		163183	6440
HPRD ID		08776	01520
Ensembl ID		ENSG00000181392	ENSG00000168484
Uniprot IDs		Q8N205	P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?		ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Potassium Ion Transport Regulation Of Dendrite Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Locomotion Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cuticle Development Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Cornification Protein Polyubiquitination Cytoplasmic Transport Establishment Of Epithelial Cell Apical/basal Polarity Progesterone Receptor Signaling Pathway Viral Life Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Glucocorticoid Receptor Signaling Pathway Vesicle Fusion With Golgi Apparatus Cellular Macromolecule Catabolic Process Positive Regulation Of Intracellular Transport T Cell Chemotaxis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Establishment Of Monopolar Cell Polarity Proteasomal Protein Catabolic Process Establishment Of Localization In Cell Protein Targeting To Lysosome Regulation Of Membrane Potential Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling Alternative MRNA Splicing, Via Spliceosome
Tagcloud ?			activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic
Tagcloud (Difference) ?			activating adenocarcinomas alveolar cdkn2a conditional deaths devastating embryogenesis epithelium foxm1 g12d ikbkb jnk jnk1 jun k kras lung myc nfkb1 nfkb2 oncogene pttg1 ras rela respiratory stimulates sufficient transgenic
Tagcloud (Intersection) ?