SEC22A and LPAR6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEC22A	LPAR6
Description		SEC22 homolog A, vesicle trafficking protein	lysophosphatidic acid receptor 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Membrane Fusion	Blastocyst Hatching Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		COPII-mediated vesicle transport	G alpha (q) signalling events P2Y receptors
Drugs			Promethazine
Diseases			Localized autosomal recessive hypotrichosis Woolly hair, including: Autosomal-dominant woolly hair (ADWH); Autosomal-recessive woolly hair (ARWH); Autosomal-recessive woolly hair with or without hypotrichosis
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Lymphocyte count ( 32888494)
Interacting Genes		108 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDAF1 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB1 PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC10A1 SLC14A2 SLC18A1 SLC30A2 SLC35H1 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27	4 interacting genes: EMP1 RPRM SEC22A SMIM3
Entrez ID		26984	10161
HPRD ID		15313	16465
Ensembl ID		ENSG00000121542	ENSG00000139679
Uniprot IDs		Q96IW7	B3KVQ5 P43657
PDB IDs			9ITB 9ITE
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Lysosomal Membrane PH-gated Chloride Channel Activity Transmembrane Transport Pattern Recognition Receptor Activity Ascorbate Homeostasis Icosanoid Biosynthetic Process Endoplasmic Reticulum-autophagosome Adaptor Activity Transmembrane Monodehydroascorbate Reductase Activity D-mannose Binding
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