SYNE4 and MARCH2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYNE4	MARCH2
Gene Name		spectrin repeat containing, nuclear envelope family member 4	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane LINC Complex	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function		Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Endocytosis Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	8 interactors: CCDC155 CDC34 FATE1 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H
Entrez ID		163183	51257
HPRD ID		08776	14361
Ensembl ID		ENSG00000181392	ENSG00000099785
Uniprot IDs		Q8N205	Q9P0N8
PDB IDs
Enriched GO Terms of Interacting Partners?		ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction	Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Macromolecule Catabolic Process Establishment Of Epithelial Cell Apical/basal Polarity Cell Cycle Process Positive Regulation Of Inclusion Body Assembly Golgi Ribbon Formation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of CAMP-mediated Signaling Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Cell Cycle Establishment Of Epithelial Cell Polarity Proteolysis Regulation Of Inclusion Body Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of CAMP-mediated Signaling Protein K11-linked Ubiquitination
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