FLNA and PSEN2

  • Number of citations of the paper that reports this interaction (PMID 9437013)
  • 18
  • Data Source:
  • HPRD (two hybrid, in vivo)

FLNA

PSEN2

Gene Name filamin A, alpha presenilin 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 82 interactors: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FAM101A FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MTNR1A MTNR1B MYOT NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RHOA SELE SH2B3 SHBG SIGLEC10 SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 2316 5664
HPRD ID 02060 02860
Ensembl ID ENSG00000196924 ENSG00000143801
Uniprot IDs P21333 Q60FE5 Q6NXF2 P49810
PDB IDs 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?