FLNA and CDC42

  • Number of citations of the paper that reports this interaction (PMID 10051605)
  • 91
  • Data Source:
  • HPRD (in vitro)

FLNA

CDC42

Gene Name filamin A, alpha cell division cycle 42
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune response to smallpox vaccine (IL-6) ( 22610502)
Protein-Protein Interactions 82 interactors: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FAM101A FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MTNR1A MTNR1B MYOT NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RHOA SELE SH2B3 SHBG SIGLEC10 SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG 144 interactors: A2M ACTR3 AHSG ANXA2 APOH ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP31 ARHGAP32 ARHGAP44 ARHGDIA ARHGDIB ARHGDIG ARHGEF11 ARHGEF25 ARHGEF6 ARHGEF7 ARRB1 ARRB2 BAIAP2 BCR BNIP2 BNIPL C14orf1 CASP3 CASP7 CBLL1 CDC42BPA CDC42BPB CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDC42SE1 CDC42SE2 CDH1 CDKN1A CFHR4 CNTNAP1 COX1 CPN1 CSN2 CSPG4 DEF6 DIAPH2 DIAPH3 DOCK7 DOCK8 DOCK9 EEF1G EIF2AK2 ERRFI1 ETFA FGD1 FGD3 FLNA FMNL2 FNBP1 GDI1 GOPC GRB2 HERC2 IQGAP1 IQGAP2 ITSN1 KAT5 KIAA2026 KTN1 LCK LGALS1 LRIF1 MAP3K10 MAP3K11 MAP3K4 MARK4 MCF2 MCF2L MCM3AP METAP2 MUC12 MYO6 MYO9A NCF2 NEK6 OCRL OPHN1 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PARD3 PARD6A PARD6B PARD6G PDE6D PGGT1B PIK3R1 PLD1 PLEKHG2 PRKCA PRKCG PRKCI PRKCZ RAC1 RAC2 RAP1GDS1 RHOJ RIOK3 RPL22 RPL23 RPS6KB1 S100A9 SH3D19 SRGAP1 SSX2IP ST13 STAU1 SYNE1 TBC1D3F TNK2 TP53 TRAF2 TRIP10 UBR1 UNC119 USP6 VAV1 VRK2 WAS WASF1 WASF2 WASL WIPF1 ZNF175 ZNF234 ZNF420
Entrez ID 2316 998
HPRD ID 02060 00309
Ensembl ID ENSG00000196924 ENSG00000070831
Uniprot IDs P21333 Q60FE5 Q6NXF2 B4E1U9 E7ETU3 P60953
PDB IDs 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH 1A4R 1AJE 1AM4 1AN0 1CEE 1CF4 1DOA 1E0A 1EES 1GRN 1GZS 1KI1 1KZ7 1KZG 1NF3 2ASE 2DFK 2KB0 2NGR 2ODB 2QRZ 2WM9 2WMN 2WMO 3GCG 3QBV 3VHL 4DID 4ITR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
abolished  adapter  adjacent  autophosphorylation  coprecipitate  coprecipitation  detailed  explained  fragment  gtpase  hck  homology  identity  modeling  mutational  nak  nck  nef  p21  pak  paks  plasmon  resonance  sh3  src  subset  termed  threonine  uncertain 
Tagcloud (Difference) ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
abolished  adapter  adjacent  autophosphorylation  coprecipitate  coprecipitation  detailed  explained  fragment  gtpase  hck  homology  identity  modeling  mutational  nak  nck  nef  p21  pak  paks  plasmon  resonance  sh3  src  subset  termed  threonine  uncertain 
Tagcloud (Intersection) ?