PSEN2 and CASP7

  • Number of citations of the paper that reports this interaction (PMID 9219695)
  • 38
  • Data Source:
  • HPRD (in vivo)

PSEN2

CASP7

Gene Name presenilin 2 caspase 7, apoptosis-related cysteine peptidase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 60 interactors: AR ARHGDIA BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP10 CASP2 CASP3 CASP8 CASP9 CAST CDC42 CFLAR CLSPN COPS6 CTSG DCTN1 DFFA DSP EIF2AK2 GOLGA3 GORASP1 GZMB HSPA5 KRT18 LYN MAPT MAX MEF2A MEF2D NEDD4 PARP1 PLA2G4B PRKCZ PSEN1 PSEN2 PSIP1 PSME3 PTGES3 PTMA RAC1 RAD21 RAD51 RASA1 RB1 RNF7 ROCK1 SAT1 SP1 SPTAN1 SRF STAT1 STK24 TERF1 TNFRSF1A UBE4B VIM XIAP
Entrez ID 5664 840
HPRD ID 02860 03457
Ensembl ID ENSG00000143801 ENSG00000165806
Uniprot IDs P49810 B4DWA2 P55210
PDB IDs 1F1J 1GQF 1I4O 1I51 1K86 1K88 1KMC 1MIA 1SHJ 1SHL 2QL5 2QL7 2QL9 2QLB 2QLF 2QLJ 3EDR 3H1P 3IBC 3IBF 3R5K 4FDL 4FEA 4HQ0 4HQR 4JB8 4JJ8 4JR1 4JR2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
balb  casp3  casp8  caspase3  closure  d10  d5  d7  dermal  execution  extrinsic  fasr  harvested  healing  innovation  intersect  intrinsic  mechanistically  mucosal  preprogrammed  punch  scarring  therapeutics  tnfrsf1b  tongue  tradd  trp53  wound  wounds 
Tagcloud (Difference) ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
balb  casp8  caspase3  closure  d10  d5  d7  dermal  execution  extrinsic  fasr  harvested  healing  innovation  intersect  intrinsic  mechanistically  mucosal  preprogrammed  punch  scarring  therapeutics  tnfrsf1b  tongue  tradd  trp53  wound  wounds 
Tagcloud (Intersection) ?
casp3