PSEN2 and NOS3

  • Number of citations of the paper that reports this interaction (PMID 21163940)
  • 13
  • Data Source:
  • BioGRID (two hybrid)

PSEN2

NOS3

Gene Name presenilin 2 nitric oxide synthase 3 (endothelial cell)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 46 interactors: A2M ACTN2 ACTN4 AGTR1 AKT1 APOE APP BDKRB2 BDNF CALM1 CAV1 CDC37 CEP55 EDNRB EFEMP1 EFEMP2 ELAVL1 ELAVL3 EXOC6 EXOSC1 FIS1 GCDH GOLGA2 H3F3A HSP90AA1 HTRA1 IMMT KANK2 MAGEA11 MAST1 MPRIP NMT1 NOSIP NOSTRIN PAXIP1 PI4K2A PPP2R5A PSEN1 PSEN2 RNF31 RNF32 SP1 ST13 TECR TXNDC11 UMPS
Entrez ID 5664 4846
HPRD ID 02860 01224
Ensembl ID ENSG00000143801 ENSG00000164867
Uniprot IDs P49810 A0S0A6 P29474
PDB IDs 1M9J 1M9K 1M9M 1M9Q 1M9R 1NIW 2LL7 3EAH 3NOS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
antidepressants  attacks  bed  favorable  genotype  genotypes  gg  glu298asp  gt  headaches  instructed  invited  medications  migraine  month  night  nortriptyline  numerical  participate  polymorphism  prophylaxis  rating  rd  st  tcas  tricyclic  tt  verbal 
Tagcloud (Difference) ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
antidepressants  attacks  bed  favorable  genotype  genotypes  gg  glu298asp  gt  headaches  instructed  invited  medications  migraine  month  night  nortriptyline  numerical  participate  polymorphism  prophylaxis  rating  rd  st  tcas  tricyclic  tt  verbal 
Tagcloud (Intersection) ?