PSEN2 and FLNB

  • Number of citations of the paper that reports this interaction (PMID 9437013)
  • 18
  • Data Source:
  • BioGRID (two hybrid, pull down)
  • HPRD (two hybrid, in vivo, in vitro)

PSEN2

FLNB

Gene Name presenilin 2 filamin B, beta
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065)
  • Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 17 interactors: ASB2 ATF7IP FBLIM1 FLNA GP1BA ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 RAD21 SMURF2 TRIM55 TSHR
Entrez ID 5664 2317
HPRD ID 02860 04543
Ensembl ID ENSG00000143801 ENSG00000136068
Uniprot IDs P49810 E7EN95 O75369
PDB IDs 2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
actionable  algorithms  asf1  assuming  candidates  distinguishing  driver  genomes  grm1  hcf1  hierarchically  interpreting  involve  machinery  modules  neutral  organized  passenger  pou2f1  precisely  presents  prkcz  psnv  psnvs  snvs  thousands  uncovered  unexpectedly  ways 
Tagcloud (Difference) ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
actionable  algorithms  asf1  assuming  candidates  distinguishing  driver  genomes  grm1  hcf1  hierarchically  interpreting  involve  machinery  modules  neutral  organized  passenger  pou2f1  precisely  presents  prkcz  psnv  psnvs  snvs  thousands  uncovered  unexpectedly  ways 
Tagcloud (Intersection) ?