FLNA and BRCA2

  • Number of citations of the paper that reports this interaction (PMID 11602572)
  • 15
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology, two hybrid)
  • HPRD (in vivo, two hybrid, in vitro)

FLNA

BRCA2

Gene Name filamin A, alpha breast cancer 2, early onset
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 82 interactors: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FAM101A FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MTNR1A MTNR1B MYOT NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RHOA SELE SH2B3 SHBG SIGLEC10 SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG 34 interactors: ATM ATR BCCIP BRCA1 BUB1B C11orf30 CCNA2 CCNE1 CDK1 CDK2 CFAP52 CHEK2 DMC1 FANCD2 FANCE FANCG FLNA H2AFX HMG20B HNRNPC KAT2B MAGED1 NEDD4 PALB2 PLK1 RAD51 RPA1 SERPINH1 SHFM1 SMAD3 STAT5A TP53 UQCC1 USP11
Entrez ID 2316 675
HPRD ID 02060 02554
Ensembl ID ENSG00000196924 ENSG00000139618
Uniprot IDs P21333 Q60FE5 Q6NXF2 P51587
PDB IDs 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH 1N0W 3EU7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
185delag  5677insa  adriamycin  brca1  breaks  camptothecin  cip1  clones  confer  doubling  du  germ  insbrca1  mdm  obvious  parental  probands  prostate  slightly  stably  strand  susceptibility  taxol  transfected  transgenes  vector  virtue  waf1  wtbrca1 
Tagcloud (Difference) ?
actin  acts  aggregation  bilateral  calcineurin  cortical  cytoskeleton  defects  downregulation  heterotopia  isoforms  knockdown  lateral  lining  linking  malformation  migration  periventricular  ph  prevented  progenitor  radial  rcan1  rearrangement  regulators  shrna  underlie  upstream  ventricles 
185delag  5677insa  adriamycin  brca1  breaks  camptothecin  cip1  clones  confer  doubling  du  germ  insbrca1  mdm  obvious  parental  probands  prostate  slightly  stably  strand  susceptibility  taxol  transfected  transgenes  vector  virtue  waf1  wtbrca1 
Tagcloud (Intersection) ?