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NINL and MCM10
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NINL
MCM10
Gene Name
ninein-like
minichromosome maintenance complex component 10
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Microtubule Organizing Center
Cytosol
Microtubule
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
Calcium Ion Binding
DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Cell Proliferation
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
Regulation of DNA replication
M/G1 Transition
Activation of the pre-replicative complex
Cell Cycle, Mitotic
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Protein-Protein Interactions
45 interactors:
AKAP17A
APEX2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
RBM41
RCOR3
RGS2
RIBC2
SH2D4A
SH3BP5L
SPERT
SYT17
TCEANC
TCEB3
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
32 interactors:
APP
CALCOCO2
CCDC85B
CCND1
CCND3
CDC45
CDC5L
CDC6
CDC7
CDK6
CDKN1A
CDKN2A
CEP70
CEP72
DPPA2
GOLGA2
HAUS1
HOOK2
IKBKG
KRT15
MCM2
MCM3
MCM6
MCM7
NINL
ORC2
ORC3
ORC4
TRIM37
VPRBP
ZBTB43
ZBTB8A
Entrez ID
22981
55388
HPRD ID
11120
11297
Ensembl ID
ENSG00000101004
ENSG00000065328
Uniprot IDs
Q9Y2I6
Q7L590
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Gene Expression
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Peptidyl-lysine Modification
Protein Acetylation
Cellular Nitrogen Compound Metabolic Process
Chromatin Organization
Protein Localization To Chromatin
Chromosome Organization
Cell Cycle
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Chromatin Modification
Histone Modification
Regulation Of Transcription, DNA-templated
Negative Regulation Of Muscle Contraction
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Organelle Organization
Mitotic Spindle Assembly Checkpoint
Spindle Assembly Checkpoint
Protein Localization To Chromosome
Cell Cycle Process
Mitotic Spindle Checkpoint
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Chromosome Segregation
Mitotic Nuclear Division
Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway
Ubiquitin-dependent Endocytosis
Regulation Of Metaphase Plate Congression
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Spindle Checkpoint
Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Muscle Cell Differentiation
Regulation Of Nitrogen Compound Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle
Cell Cycle Process
DNA Replication Initiation
DNA-dependent DNA Replication
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
DNA Metabolic Process
Regulation Of Cell Cycle Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Macromolecule Biosynthetic Process
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
DNA Duplex Unwinding
DNA Geometric Change
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA Unwinding Involved In DNA Replication
Cellular Nitrogen Compound Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of Mitotic Cell Cycle
Cell Division
Biosynthetic Process
DNA Conformation Change
Double-strand Break Repair Via Break-induced Replication
Nitrogen Compound Metabolic Process
Organelle Organization
Chromosome Organization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cellular Response To DNA Damage Stimulus
Cell Cycle Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Phosphorylation
Tagcloud
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Difference)
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Intersection)
?