NINL and FAM107A

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	FAM107A
Gene Name		ninein-like	family with sequence similarity 107, member A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Microtubule	Nucleus Neuron Projection
	Molecular Function	Calcium Ion Binding	Molecular_function
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Regulation Of Cell Growth
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	24 interactors: BEGAIN CALCOCO2 CANX CCDC136 CCDC85B EFEMP2 FSD2 HOOK2 KRT15 KRT19 KRT40 KRTAP4-12 LDOC1 LZTS2 MID2 NINL PNMA1 RINT1 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47
Entrez ID		22981	11170
HPRD ID		11120	09753
Ensembl ID		ENSG00000101004	ENSG00000168309
Uniprot IDs		Q9Y2I6	O95990 Q6IAM1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process	Positive Regulation Of NF-kappaB Transcription Factor Activity
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