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NINL and KRT1
Number of citations of the paper that reports this interaction (PubMedID
25910212
)
47
Data Source:
BioGRID
(two hybrid)
NINL
KRT1
Description
ninein like
keratin 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Microtubule
Cornified Envelope
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Membrane
Keratin Filament
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Molecular Function
Calcium Ion Binding
Protein Binding
Metal Ion Binding
Protein Binding
Carbohydrate Binding
Structural Constituent Of Skin Epidermis
Signaling Receptor Activity
Protein Heterodimerization Activity
Biological Process
Microtubule Anchoring At Centrosome
Complement Activation, Lectin Pathway
Response To Oxidative Stress
Peptide Cross-linking
Keratinization
Fibrinolysis
Intermediate Filament Organization
Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Protein Heterotetramerization
Establishment Of Skin Barrier
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Zinc
Copper
Zinc acetate
Diseases
Ichthyosis hystrix, Curth-Macklin type
Epidermolytic palmoplantar keratoderma (EPPK)
Striate palmoplantar keratoderma
Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
GWAS
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Interacting Genes
52 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSC1
TSPYL4
UTP14A
YJU2B
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
54 interacting genes:
-
AMOTL2
CALB2
CSTA
DSP
EVPL
F12
FANCA
FANCC
FFAR2
GOLGA2
GOLGA6L9
HAUS1
HMG20A
HOOK2
IVL
KNG1
KRT13
KRT14
KRT15
KRT16
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT40
KRT5
LINC00839
LORICRIN
MBL2
NINL
NUP62
OGT
PI3
PRKCE
RINT1
RNF26
SGTB
TFIP11
TLCD4
TRIM54
U2AF1
UBE3A
YWHAQ
Entrez ID
22981
3848
HPRD ID
11120
00763
Ensembl ID
ENSG00000101004
ENSG00000167768
Uniprot IDs
Q9Y2I6
P04264
PDB IDs
4ZRY
6E2J
6UUI
Enriched GO Terms of Interacting Partners
?
Mitotic Spindle Pole
Nucleus
Protein Binding
Chromosome, Centromeric Region
Positive Regulation Of Mitotic Sister Chromatid Segregation
Spindle Pole
Regulation Of Metaphase Plate Congression
Kinetochore
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Histone Acetyltransferase Complex
Positive Regulation Of Chromosome Segregation
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Attachment Of Spindle Microtubules To Kinetochore
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Histone H4K16 Acetyltransferase Activity
Spindle Microtubule
Protein Localization To Chromosome
Regulation Of Sister Chromatid Segregation
Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Regulation Of RNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle
Cytoskeleton
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Spindle Midzone Assembly
Histone H4 Acetyltransferase Activity
Peptidyl-lysine Acetylation
Negative Regulation Of Cell Cycle Phase Transition
Zinc Ion Binding
Regulation Of Chromosome Segregation
Regulation Of Mitotic Sister Chromatid Separation
RNA Splicing
Centrosome
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament
Structural Molecule Activity
Epithelial Cell Differentiation
Cytoskeleton Organization
Supramolecular Fiber Organization
Morphogenesis Of An Epithelium
Tissue Morphogenesis
Cytoskeleton
Organelle Organization
Cornified Envelope
Peptide Cross-linking
Structural Constituent Of Cytoskeleton
Anatomical Structure Morphogenesis
Cell Differentiation
Keratinocyte Differentiation
Extracellular Exosome
Cellular Developmental Process
Epidermis Development
Cytosol
Epidermal Cell Differentiation
Keratinization
Hair Cycle
Developmental Process
Centrosome Cycle
Intermediate Filament Cytoskeleton
Hair Follicle Morphogenesis
Microtubule Organizing Center Organization
Protein Localization To Perinuclear Region Of Cytoplasm
Tissue Development
Cell Surface Pattern Recognition Receptor Signaling Pathway
Fanconi Anaemia Nuclear Complex
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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