NINL and RGS2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	RGS2
Gene Name		ninein-like	regulator of G-protein signaling 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Microtubule	Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Neuron Projection
	Molecular Function	Calcium Ion Binding	GTPase Activator Activity Protein Binding Calmodulin Binding Beta-tubulin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Regulation Of Translation Cell Cycle Spermatogenesis Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Phospholipase Activity Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Microtubule Polymerization Termination Of G-protein Coupled Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Smooth Muscle Positive Regulation Of Cardiac Muscle Contraction Regulation Of Adrenergic Receptor Signaling Pathway
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	58 interactors: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CHD3 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KIAA1377 KLK8 LIG1 LRFN1 METTL18 MON1A MTUS2 NINL NIPSNAP1 PARK2 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX
Entrez ID		22981	5997
HPRD ID		11120	02917
Ensembl ID		ENSG00000101004	ENSG00000116741
Uniprot IDs		Q9Y2I6	P41220
PDB IDs			2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process	Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Platelet Activation Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Response To Wounding Blood Coagulation G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Hemostasis Wound Healing Cell-cell Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Nervous System Development Regulation Of Cyclase Activity Activation Of Adenylate Cyclase Activity Signaling Response To Stress Neurotrophin Signaling Pathway Cell Communication Regulation Of Phosphorylation Dopamine Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Developmental Process Positive Regulation Of Adenylate Cyclase Activity Regulation Of Kinase Activity Response To Organic Substance Cellular Response To Stimulus Regulation Of Muscle Contraction Anatomical Structure Development Regulation Of CAMP Biosynthetic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Positive Regulation Of Hydrolase Activity Cell Activation Membrane Organization Regulation Of CAMP Metabolic Process Regulation Of Protein Phosphorylation System Development Positive Regulation Of Lyase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Budding Adrenergic Receptor Signaling Pathway
Tagcloud ?			3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Difference) ?			3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Intersection) ?