NINL and SYT17

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	SYT17
Gene Name		ninein-like	synaptotagmin XVII
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Microtubule	Trans-Golgi Network Synaptic Vesicle Membrane
	Molecular Function	Calcium Ion Binding	Transporter Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Exocytosis
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Alcohol dependence ( 21876473)
Protein-Protein Interactions		45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	18 interactors: APP APTX CCDC85B CEP63 CEP70 CHMP4A FAM9B GMCL1 IKZF1 MEOX1 MEOX2 MID2 NIF3L1 NINL RUNDC3A SSX2IP TRAF2 TSC22D4
Entrez ID		22981	51760
HPRD ID		11120	17425
Ensembl ID		ENSG00000101004
Uniprot IDs		Q9Y2I6	H3BN78 H3BRH9 Q9BSW7
PDB IDs			2ENP
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process	Somite Specification Segment Specification G2/M Transition Of Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neuron Death Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Polynucleotide 3' Dephosphorylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Mitotic Cell Cycle Somitogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Pattern Specification Cell Cycle Centrosome Organization Negative Regulation Of Autophagic Vacuole Assembly Dihydrobiopterin Metabolic Process Collateral Sprouting In Absence Of Injury Somite Development Regulation Of Multicellular Organism Growth Negative Regulation Of Cellular Metabolic Process Microtubule Organizing Center Organization Sclerotome Development Response To Oxidative Stress Positive Regulation Of Macromolecule Biosynthetic Process Segmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Microtubule-based Transport Intraciliary Transport Involved In Cilium Morphogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cytoskeleton-dependent Intracellular Transport Positive Regulation Of NK T Cell Differentiation Viral Budding Via Host ESCRT Complex Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Protein Binding
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