NINL and CLEC1B

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		NINL	CLEC1B
Description		ninein like	C-type lectin domain family 1 member B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule	Plasma Membrane Cell Surface Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Microtubule Anchoring At Centrosome	Defense Response Signal Transduction Cell Surface Receptor Signaling Pathway Platelet Formation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	GPVI-mediated activation cascade Heme signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Blood protein levels ( 30072576) Malaria ( 31844061)
Interacting Genes		52 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSC1 TSPYL4 UTP14A YJU2B ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	2 interacting genes: NINL RACK1
Entrez ID		22981	51266
HPRD ID		11120	09490
Ensembl ID		ENSG00000101004	ENSG00000165682
Uniprot IDs		Q9Y2I6	Q9P126
PDB IDs			2C6U 3WSR 3WWK
Enriched GO Terms of Interacting Partners?		Mitotic Spindle Pole Nucleus Protein Binding Chromosome, Centromeric Region Positive Regulation Of Mitotic Sister Chromatid Segregation Spindle Pole Regulation Of Metaphase Plate Congression Kinetochore Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone Acetyltransferase Complex Positive Regulation Of Chromosome Segregation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Histone H4K16 Acetyltransferase Activity Spindle Microtubule Protein Localization To Chromosome Regulation Of Sister Chromatid Segregation Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of RNA Metabolic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cytoskeleton Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Negative Regulation Of Cell Cycle Phase Transition Zinc Ion Binding Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation RNA Splicing Centrosome	IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Negative Regulation Of Translational Elongation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Positive Regulation Of Membrane Depolarization Positive Regulation Of Gastrulation Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Positive Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Translational Elongation Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Mitochondrial Depolarization Ion Channel Inhibitor Activity Regulation Of Golgi To Plasma Membrane Protein Transport BH3 Domain Binding Protein Tyrosine Kinase Inhibitor Activity Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Regulation Of Gastrulation Positive Regulation Of Embryonic Development Translation Regulator Activity Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Phagocytosis Regulation Of Establishment Of Cell Polarity Regulation Of Mitochondrial Depolarization Regulation Of Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Protein Serine/threonine Kinase Inhibitor Activity Small Ribosomal Subunit Microtubule Anchoring Phagocytic Cup Negative Regulation Of Protein Binding Cyclin Binding Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Rescue Of Stalled Ribosome Negative Regulation Of Smoothened Signaling Pathway Cytosolic Small Ribosomal Subunit SH2 Domain Binding Gastrulation Regulation Of Protein Binding Regulation Of Membrane Depolarization Protein Kinase C Binding Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Pigmentation Ribosome Disassembly Negative Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Glucose Stimulus Translational Elongation Negative Regulation Of Endocytosis
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