NINL and TCEANC

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)

		NINL	TCEANC
Gene Name		ninein-like	transcription elongation factor A (SII) N-terminal and central domain containing
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Organizing Center Cytosol Microtubule	Nucleus
	Molecular Function	Calcium Ion Binding	DNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of DNA-templated Transcription, Elongation
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	36 interactors: APP ATXN1 BRCA1 CARD9 CCDC85B CRACR2B CSRNP1 DAB1 FAM9B FBXO25 FSD2 GOLGA2 HMBOX1 IKBKG KIFC3 KRTAP10-7 KRTAP4-2 KRTAP5-9 LURAP1 MAGEA11 MEOX1 MID1 NAB2 NEDD4 NINL PNMA1 RAD54B RNF219 SPERT SSNA1 TARBP2 TRAF2 VAC14 VPS52 ZBTB14 ZKSCAN7
Entrez ID		22981	170082
HPRD ID		11120	19501
Ensembl ID		ENSG00000101004	ENSG00000176896
Uniprot IDs		Q9Y2I6	Q8N8B7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process	Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cytokine Production Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Kinase Activity Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Adult Locomotory Behavior Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Gene Expression Regulation Of Cytokine Production Nucleobase-containing Compound Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Cellular Metabolic Process Activation Of Innate Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein K63-linked Ubiquitination Regulation Of Protein Binding Immune Response NIK/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Regulation Of NIK/NF-kappaB Signaling RNA Metabolic Process Negative Regulation Of Biosynthetic Process Adult Behavior Protein Autoubiquitination Protein Polyubiquitination Cellular Nitrogen Compound Metabolic Process Regulation Of Signal Transduction
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