SOS1 and FRS2

  • Number of citations of the paper that reports this interaction (PMID 9182757)
  • 147
  • Data Source:
  • HPRD (in vitro, in vivo)

SOS1

FRS2

Gene Name son of sevenless homolog 1 (Drosophila) fibroblast growth factor receptor substrate 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 52 interactors: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SNX18 SNX9 SPTAN1 TNIK ZAP70 22 interactors: CBL CRK DDR1 FGFR1 GAB1 GRB2 INSR KDR MAPK1 NCK1 NTRK1 NTRK2 NTRK3 PAK1 PRKCI PRKCZ PTPN11 PTPRF RET RND1 SOS1 SRC
Entrez ID 6654 10818
HPRD ID 01681 06372
Ensembl ID ENSG00000115904 ENSG00000166225
Uniprot IDs G5E9C8 Q07889 L7RTG7 Q8WU20
PDB IDs 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY 1XR0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
adapter  adenoviruses  bdnf  branching  cascades  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
Tagcloud (Difference) ?
accordingly  antisense  b9  cascade  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
adapter  adenoviruses  bdnf  branching  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
Tagcloud (Intersection) ?
cascades