SOS1 and PLCG1

  • Number of citations of the paper that reports this interaction (PMID 10913276)
  • 10
  • Data Source:
  • HPRD (in vitro)

SOS1

PLCG1

Gene Name son of sevenless homolog 1 (Drosophila) phospholipase C, gamma 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 52 interactors: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SNX18 SNX9 SPTAN1 TNIK ZAP70 106 interactors: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GNB2L1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 6654 5335
HPRD ID 01681 01398
Ensembl ID ENSG00000115904 ENSG00000124181
Uniprot IDs G5E9C8 Q07889 P19174 Q4LE43 Q9UFY1
PDB IDs 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Difference) ?
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Intersection) ?