SMARCE1 and CEP70

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SMARCE1	CEP70
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	centrosomal protein 70kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Ligand-dependent Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: AMOTL2 AR ARID2 BAZ1B BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NL NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARA RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1	134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12
Entrez ID		6605	80321
HPRD ID		04382	16779
Ensembl ID		ENSG00000073584	ENSG00000114107
Uniprot IDs		Q969G3	B7Z2D2 Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Transcription From RNA Polymerase II Promoter Chromosome Organization RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Response To Steroid Hormone Stimulus Hormone-mediated Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Gland Development Cellular Response To Organic Cyclic Compound Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Steroid Hormone Negative Regulation Of Nucleic Acid-templated Transcription Organ Development Negative Regulation Of RNA Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process
Tagcloud ?		acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Difference) ?		acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Intersection) ?