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EEF1A1 and ACTB
Number of citations of the paper that reports this interaction (PubMedID
11854414
)
51
Data Source:
HPRD
(in vivo)
EEF1A1
ACTB
Description
eukaryotic translation elongation factor 1 alpha 1
actin beta
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Ribosome
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cytosolic Ribosome
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Kinetochore
Chromatin
Nucleosome
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Brush Border
Cell-cell Junction
Adherens Junction
Focal Adhesion
Actin Cytoskeleton
Membrane
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Lamellipodium
Axon
Cortical Cytoskeleton
Vesicle
Protein-containing Complex
Brahma Complex
NuA4 Histone Acetyltransferase Complex
Cytoplasmic Ribonucleoprotein Granule
Apical Junction Complex
Calyx Of Held
Synapse
Extracellular Exosome
Tight Junction
NpBAF Complex
NBAF Complex
Blood Microparticle
Dense Body
Schaffer Collateral - CA1 Synapse
Presynapse
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
BBAF Complex
GBAF Complex
Ribonucleoprotein Complex
Molecular Function
TRNA Binding
Nucleotide Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
GTP Binding
Hydrolase Activity
Kinase Activator Activity
Kinase Binding
Protein Kinase Binding
Molecular Adaptor Activity
Nucleotide Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Kinesin Binding
Protein Kinase Binding
Nitric-oxide Synthase Regulator Activity
Tat Protein Binding
Nucleosomal DNA Binding
Identical Protein Binding
Tau Protein Binding
Nitric-oxide Synthase Binding
Structural Constituent Of Postsynaptic Actin Cytoskeleton
Transporter Regulator Activity
Biological Process
Translation
Translational Elongation
Host-mediated Activation Of Viral Genome Replication
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of Chaperone-mediated Autophagy
Morphogenesis Of A Polarized Epithelium
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Cytoskeleton Organization
Establishment Or Maintenance Of Cell Polarity
Axonogenesis
Positive Regulation Of Cell Population Proliferation
Substantia Nigra Development
Regulation Of Mitotic Metaphase/anaphase Transition
Adherens Junction Assembly
Maintenance Of Blood-brain Barrier
Regulation Of Apoptotic Process
Apical Protein Localization
Positive Regulation Of T Cell Differentiation
Negative Regulation Of Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of DNA-templated Transcription
Cell Motility
Regulation Of Norepinephrine Uptake
Positive Regulation Of Norepinephrine Uptake
Regulation Of Cell Cycle
Regulation Of G0 To G1 Transition
Platelet Aggregation
Protein Localization To Adherens Junction
Cellular Response To Cytochalasin B
Postsynaptic Actin Cytoskeleton Organization
Regulation Of Transepithelial Transport
Regulation Of Synaptic Vesicle Endocytosis
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Double-strand Break Repair
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
SARS-CoV-1 modulates host translation machinery
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Gap junction degradation
Formation of annular gap junctions
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
HATs acetylate histones
Prefoldin mediated transfer of substrate to CCT/TriC
Folding of actin by CCT/TriC
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
Adherens junctions interactions
Adherens junctions interactions
Recycling pathway of L1
Recycling pathway of L1
VEGFA-VEGFR2 Pathway
Interaction between L1 and Ankyrins
Interaction between L1 and Ankyrins
Cell-extracellular matrix interactions
B-WICH complex positively regulates rRNA expression
RHO GTPases activate IQGAPs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
RHO GTPases Activate Formins
MAP2K and MAPK activation
UCH proteinases
DNA Damage Recognition in GG-NER
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Clathrin-mediated endocytosis
RHOF GTPase cycle
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of CDH1 Function
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Factors involved in megakaryocyte development and platelet production
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of the non-canonical BAF (ncBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Quercetin
Phenethyl Isothiocyanate
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Global electrical heterogeneity phenotypes (
29622589
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Lymphocyte count (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Relative hand skill in reading disability (
24068947
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Triglyceride levels (
32203549
)
Interacting Genes
144 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCL18
CDC25A
CDKN1A
CEBPA
CKS2
CLIC6
COX17
CRADD
CRCT1
CREBBP
CSRP2
CTIF
DARS1
DCTN1
DIABLO
DLEU1
DNMT1
DNMT3A
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HOXA1
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
OGT
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SF3B4
SFN
SHBG
SMAD2
SMAD4
SMN1
SPATS2L
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSC2
TSPY1
TSPYL2
TTLL12
TTR
TXNIP
UBQLN4
USP40
VHL
WARS1
WEE2-AS1
XPO5
XRN2
YJU2B
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
161 interacting genes:
A2M
ABLIM1
ABRA
ACD
ACTC1
ACTG1
ALOX5
ANXA7
AQP2
AR
ARPC1B
ATF7IP
BBS4
BCL2L1
CAP1
CAPZA1
CCN2
CCT2
CCT4
CCT5
CCT8
CDC37
CDK5R2
CDKN1A
CDKN2A
CFL1
CFL2
CLIC4
CLIC6
CLNS1A
CNN2
CORO1A
CORO7
COTL1
CPNE1
CPNE2
CPNE4
CREBBP
CSNK1A1
CSNK2B
DMTN
DNASE1
DSCR9
DSTN
DUSP19
DYNLL1
EEF1A1
EHHADH
EMD
ERG
EZR
FABP4
FHL3
FLII
FXR1
GAPDH
GNA12
GSN
H2AX
HCK
HIP1R
HMMR
HNRNPAB
HNRNPD
HNRNPU
HSD17B4
HSPB2
HTR6
KHDRBS1
LASP1
LCOR
LGALS13
LINC01554
LINC02582
LMNA
LMOD1
LRRK2
LYN
MAP1B
MAP2
MAPT
MRGBP
MTNR1A
MX1
MYO18B
MYO1E
MYOC
NCALD
NCF1
NDEL1
NEBL
NOS2
NRAP
NSMAF
NT5E
NTAQ1
OGT
P2RX7
PCYT1A
PDIA2
PDLIM5
PFDN1
PFDN4
PFN1
PFN2
PHACTR4
PLD1
PLD2
PLG
POLR2A
POT1
PRKCD
PROSER2
PTN
PTPRF
RAB4A
RAC1
RAC2
RCC1
RPL10A
S100A11
SAMHD1
SCN10A
SHBG
SMAD3
SMAD9
SMARCA4
SMN1
SPTAN1
SPTB
SPTBN2
SRPK2
SSH1
SSH2
SSH3
STX4
SUMO2
SYNJ2BP
TANC1
TGM2
TINF2
TK1
TMSB4X
TMSB4XP1
TMSB4XP4
TNNI2
TPM1
TPM2
TPM3
TRIM15
TSHR
TTR
UBC
UBE2I
UBE3A
VHL
VSNL1
WASF1
WASF2
WASF3
XPO6
Entrez ID
1915
60
HPRD ID
00559
00032
Ensembl ID
ENSG00000156508
ENSG00000075624
Uniprot IDs
P68104
Q6IPS9
P60709
Q1KLZ0
PDB IDs
3C5J
6ZMO
8G60
8G6J
3BYH
3D2U
3J82
3LUE
6ANU
6ICT
6ICV
6LTJ
6MBJ
6MBK
6MBL
6NBW
6OX0
6OX1
6OX2
6OX3
6OX4
6OX5
6V62
6V63
6WK1
6WK2
7AS4
7P1H
7QJ6
7QJ9
7VDV
7W28
7W29
7Y8R
7ZTC
7ZTD
8COG
8DNH
8IB8
8OI8
8OID
8QR1
8RTT
8RTY
8RU2
8RX1
8UAU
8VRD
8VRJ
8VRK
8X15
8X19
8X1C
8XVG
8XVT
9B2Z
9C57
9C62
9C6N
9FJM
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Apoptotic Process
Cell Death
Programmed Cell Death
Regulation Of Programmed Cell Death
Cytosol
Negative Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Kinase Activity
Negative Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Nucleic Acid Metabolic Process
Negative Regulation Of Phosphorylation
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Apoptotic Signaling Pathway
BBSome
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Localization To Nucleus
Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
TORC1 Signaling
Protein-containing Complex
Nucleus
Macromolecule Biosynthetic Process
Melanosome Transport
Tau Protein Binding
Regulation Of Developmental Process
RNA Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Establishment Of Melanosome Localization
Pigment Granule Transport
Negative Regulation Of Protein Phosphorylation
Cellular Response To Stress
Melanosome Localization
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Macromolecule Metabolic Process
Positive Regulation Of Apoptotic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pigment Granule Localization
Mitochondrial Intermembrane Space
Nucleoplasm
Protein Binding
Negative Regulation Of Catalytic Activity
Histone H3K27 Acetyltransferase Activity
Negative Regulation Of Phosphate Metabolic Process
TOR Signaling
Positive Regulation Of TOR Signaling
Regulation Of Phosphorus Metabolic Process
Actin Binding
Regulation Of Cytoskeleton Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Organization
Regulation Of Actin Filament-based Process
Regulation Of Organelle Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Negative Regulation Of Supramolecular Fiber Organization
Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Actin Filament-based Process
Actin Filament Binding
Regulation Of Cellular Component Organization
Regulation Of Cellular Component Size
Actin Filament Organization
Negative Regulation Of Cytoskeleton Organization
Cytoskeleton
Negative Regulation Of Actin Filament Polymerization
Cytoplasm
Negative Regulation Of Cellular Component Organization
Cytoskeleton Organization
Supramolecular Fiber Organization
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Organelle Organization
Actin Cytoskeleton
Regulation Of Biological Quality
Negative Regulation Of Protein-containing Complex Assembly
Extracellular Exosome
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Supramolecular Fiber Organization
Cortical Actin Cytoskeleton
Regulation Of Actin Filament Depolymerization
Actin Filament
Organelle Organization
Glutamatergic Synapse
Positive Regulation Of Cellular Component Organization
Modification Of Postsynaptic Actin Cytoskeleton
Cytosol
Regulation Of Protein Localization
Regulation Of Protein Depolymerization
Negative Regulation Of Actin Filament Depolymerization
Focal Adhesion
Regulation Of Telomere Maintenance Via Telomerase
Modification Of Postsynaptic Structure
Actin Filament Capping
Postsynapse
Modification Of Synaptic Structure
Regulation Of Cellular Localization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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