EEF1A1 and SDHAF2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1A1	SDHAF2
Description		eukaryotic translation elongation factor 1 alpha 1	succinate dehydrogenase complex assembly factor 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Ribosome Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Cytosolic Ribosome Cortical Actin Cytoskeleton Ruffle Membrane Secretory Granule Lumen Extracellular Exosome Cytoplasmic Side Of Lysosomal Membrane Ficolin-1-rich Granule Lumen	Nucleolus Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Kinase Activator Activity Kinase Binding Protein Kinase Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Translation Translational Elongation Host-mediated Activation Of Viral Genome Replication Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Chaperone-mediated Autophagy	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Protein Dephosphorylation Negative Regulation Of Epithelial To Mesenchymal Transition Protein-FAD Linkage Mitochondrial Respiratory Chain Complex II Assembly Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy SARS-CoV-1 modulates host translation machinery	Maturation of TCA enzymes and regulation of TCA cycle
Drugs		Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes		144 interacting genes: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 AQP2 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCL18 CDC25A CDKN1A CEBPA CKS2 CLIC6 COX17 CRADD CRCT1 CREBBP CSRP2 CTIF DARS1 DCTN1 DIABLO DLEU1 DNMT1 DNMT3A DUSP7 DYNLL1 DYSF EIF3F EP300 EXOSC4 FAS GADD45A GADD45G HOXA1 HSPB2 HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP OGT ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP PTPRF RAB27A RAP2A RFC5 RGS12 RND1 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB5 SERPINB9 SF3B4 SFN SHBG SMAD2 SMAD4 SMN1 SPATS2L SPP1 SSR1 STAT6 STMN2 SULT1E1 SUMO2 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSC2 TSPY1 TSPYL2 TTLL12 TTR TXNIP UBQLN4 USP40 VHL WARS1 WEE2-AS1 XPO5 XRN2 YJU2B YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	6 interacting genes: CCDC90B CYP4F2 EEF1A1 ELP1 IMMT SEC22A
Entrez ID		1915	54949
HPRD ID		00559	07915
Ensembl ID		ENSG00000156508	ENSG00000167985
Uniprot IDs		P68104 Q6IPS9	Q9NX18
PDB IDs		3C5J 6ZMO 8G60 8G6J	6VAX 8DYD
Enriched GO Terms of Interacting Partners?		Cytoplasm Apoptotic Process Cell Death Programmed Cell Death Regulation Of Programmed Cell Death Cytosol Negative Regulation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Nucleic Acid Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Apoptotic Signaling Pathway BBSome Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling TORC1 Signaling Protein-containing Complex Nucleus Macromolecule Biosynthetic Process Melanosome Transport Tau Protein Binding Regulation Of Developmental Process RNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Establishment Of Melanosome Localization Pigment Granule Transport Negative Regulation Of Protein Phosphorylation Cellular Response To Stress Melanosome Localization Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Macromolecule Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pigment Granule Localization Mitochondrial Intermembrane Space Nucleoplasm Protein Binding Negative Regulation Of Catalytic Activity Histone H3K27 Acetyltransferase Activity Negative Regulation Of Phosphate Metabolic Process TOR Signaling Positive Regulation Of TOR Signaling Regulation Of Phosphorus Metabolic Process	TRNA Binding Eukaryotic Translation Elongation Factor 1 Complex TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Elongator Holoenzyme Complex Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Phylloquinone Catabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Leukotriene B4 Catabolic Process Vitamin K Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Vitamin E Metabolic Process Alkane 1-monooxygenase Activity Menaquinone Metabolic Process 20-aldehyde-leukotriene B4 20-monooxygenase Activity Fatty Acid Omega-oxidation Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Menaquinone Catabolic Process Mitochondrial Crista Junction MICOS Complex Regulation Of Chaperone-mediated Autophagy Long-chain Fatty Acid Catabolic Process Negative Regulation Of Fatty Acid Transport Host-mediated Activation Of Viral Genome Replication Arachidonate Epoxygenase Activity Omega-hydroxylase P450 Pathway SAM Complex MIB Complex Host-mediated Perturbation Of Viral Genome Replication Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Cristae Formation Kinase Activator Activity Cytoplasmic Side Of Lysosomal Membrane Vitamin K Metabolic Process TRNA Wobble Uridine Modification Epoxygenase P450 Pathway Mitochondrial Envelope Positive Regulation Of Icosanoid Secretion Ketone Catabolic Process Translation Elongation Factor Activity Renal Water Homeostasis Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Fatty Acid Transport Mitochondrial Calcium Ion Homeostasis Inorganic Ion Homeostasis Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Vitamin Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?