EEF1A1 and TSPYL2

Number of citations of the paper that reports this interaction (PMID 18649364)
7

Data Source:
HPRD (in vitro)

		EEF1A1	TSPYL2
Gene Name		eukaryotic translation elongation factor 1 alpha 1	TSPY-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Plasma Membrane
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding	RDNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus	Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cell Cycle Negative Regulation Of DNA Replication Regulation Of Signal Transduction Chromatin Modification Negative Regulation Of Cell Growth Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity
Pathways		HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	9 interactors: APTX CASK CCNB1 CDK1 CDK2 CDK4 COIL EEF1A1 GFI1B
Entrez ID		1915	64061
HPRD ID		00559	06713
Ensembl ID		ENSG00000156508	ENSG00000184205
Uniprot IDs		P68104 Q6IPS9	Q9H2G4
PDB IDs		1SYW
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity	G1/S Transition Of Mitotic Cell Cycle Response To Inorganic Substance Histone Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Chromatin Organization Positive Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Gene Expression Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division G2/M Transition Of Mitotic Cell Cycle Chromosome Organization Ventricular Cardiac Muscle Cell Development Response To Toxic Substance Protein Phosphorylation Chromatin Modification Response To Reactive Oxygen Species Regulation Of Protein Ubiquitination Ventricular Cardiac Muscle Cell Differentiation Mitotic Cell Cycle Process Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Mitotic Nuclear Envelope Disassembly Mitotic Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Heart Growth Phosphate-containing Compound Metabolic Process Nuclear Envelope Disassembly Positive Regulation Of Cell Proliferation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cardiac Muscle Cell Proliferation Cellular Macromolecule Catabolic Process Regulation Of Metabolic Process Chromosome Condensation Positive Regulation Of Organ Growth Mitotic Nuclear Division Cellular Nitrogen Compound Metabolic Process Response To Metal Ion Phosphorylation Regulation Of Cell Cycle Centrosome Cycle Regulation Of Heart Growth
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	abolishes abrogates af1 bradyzoite bradyzoites cyst cysts disseminate gondii ip1 myoblasts myosin myotubes opportunistic persist polynucleated replicate replicating restrict skmcs sustain syncytial tachyzoite tachyzoites toxoplasma toxoplasmosis upregulate vigorous vigorously
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	abolishes abrogates af1 bradyzoite bradyzoites cyst cysts disseminate gondii ip1 myoblasts myosin myotubes opportunistic persist polynucleated replicate replicating restrict skmcs sustain syncytial tachyzoite tachyzoites toxoplasma toxoplasmosis upregulate vigorous vigorously
Tagcloud (Intersection) ?