EEF1A1 and RRAS

Number of citations of the paper that reports this interaction (PubMedID 18624398)
0

Data Source:
BioGRID (two hybrid)

		EEF1A1	RRAS
Description		eukaryotic translation elongation factor 1 alpha 1	RAS related
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Ribosome Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Cytosolic Ribosome Cortical Actin Cytoskeleton Ruffle Membrane Secretory Granule Lumen Extracellular Exosome Cytoplasmic Side Of Lysosomal Membrane Ficolin-1-rich Granule Lumen	Plasma Membrane Focal Adhesion Membrane Extracellular Exosome
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Kinase Activator Activity Kinase Binding Protein Kinase Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein-containing Complex Binding
	Biological Process	Translation Translational Elongation Host-mediated Activation Of Viral Genome Replication Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Chaperone-mediated Autophagy	Leukocyte Differentiation Signal Transduction Ras Protein Signal Transduction Positive Regulation Of Endothelial Cell Migration Cell Migration Schwann Cell Migration Positive Regulation Of Angiogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Face Morphogenesis Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Schwann Cell Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Vasculogenesis
Pathways		Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy SARS-CoV-1 modulates host translation machinery	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration
Drugs		Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163) Pulse pressure ( 27618447) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27618447)
Interacting Genes		144 interacting genes: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 AQP2 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCL18 CDC25A CDKN1A CEBPA CKS2 CLIC6 COX17 CRADD CRCT1 CREBBP CSRP2 CTIF DARS1 DCTN1 DIABLO DLEU1 DNMT1 DNMT3A DUSP7 DYNLL1 DYSF EIF3F EP300 EXOSC4 FAS GADD45A GADD45G HOXA1 HSPB2 HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP OGT ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP PTPRF RAB27A RAP2A RFC5 RGS12 RND1 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB5 SERPINB9 SF3B4 SFN SHBG SMAD2 SMAD4 SMN1 SPATS2L SPP1 SSR1 STAT6 STMN2 SULT1E1 SUMO2 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSC2 TSPY1 TSPYL2 TTLL12 TTR TXNIP UBQLN4 USP40 VHL WARS1 WEE2-AS1 XPO5 XRN2 YJU2B YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	17 interacting genes: ACY3 AFDN ARAF BCL2 EEF1A1 EPHB2 MRPL36 NAV2 NCK1 PPP2CA RAF1 RALGDS RASIP1 RASSF5 SOS1 TRIM55 TRIM63
Entrez ID		1915	6237
HPRD ID		00559	01299
Ensembl ID		ENSG00000156508	ENSG00000126458
Uniprot IDs		P68104 Q6IPS9	P10301
PDB IDs		3C5J 6ZMO 8G60 8G6J	2FN4 7S0Z
Enriched GO Terms of Interacting Partners?		Cytoplasm Apoptotic Process Cell Death Programmed Cell Death Regulation Of Programmed Cell Death Cytosol Negative Regulation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Nucleic Acid Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Apoptotic Signaling Pathway BBSome Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling TORC1 Signaling Protein-containing Complex Nucleus Macromolecule Biosynthetic Process Melanosome Transport Tau Protein Binding Regulation Of Developmental Process RNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Establishment Of Melanosome Localization Pigment Granule Transport Negative Regulation Of Protein Phosphorylation Cellular Response To Stress Melanosome Localization Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Macromolecule Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pigment Granule Localization Mitochondrial Intermembrane Space Nucleoplasm Protein Binding Negative Regulation Of Catalytic Activity Histone H3K27 Acetyltransferase Activity Negative Regulation Of Phosphate Metabolic Process TOR Signaling Positive Regulation Of TOR Signaling Regulation Of Phosphorus Metabolic Process	Regulation Of Mononuclear Cell Proliferation Regulation Of Leukocyte Proliferation Signal Transduction Lymphocyte Homeostasis Regulation Of Intracellular Signal Transduction Leukocyte Homeostasis Lymphocyte Activation Pore Complex Regulation Of Phosphorus Metabolic Process Regulation Of Lymphocyte Activation Leukocyte Activation Immune System Process Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Glycolytic Process Schwann Cell Development Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation MAP Kinase Kinase Kinase Activity Negative Regulation Of ATP Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Activation B Cell Homeostasis Cell Activation Neurotrophin Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Catabolic Process Insulin-like Growth Factor Receptor Signaling Pathway Protein Modification Process Cytoplasm T Cell Homeostasis Positive Regulation Of Leukocyte Proliferation Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Intracellular Signal Transduction Regulation Of Protein-containing Complex Assembly Intracellular Signal Transduction Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Positive Regulation Of B Cell Proliferation Homeostasis Of Number Of Cells Ribosome Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Junction Positive Regulation Of Protein-containing Complex Assembly RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?