Wiki-Pi
About
Search
People
Updates
Search
ACTB and HNRNPD
Number of citations of the paper that reports this interaction (PubMedID
35831314
)
73
Data Source:
BioGRID
(biochemical, two hybrid)
ACTB
HNRNPD
Description
actin beta
heterogeneous nuclear ribonucleoprotein D
Image
GO Annotations
Cellular Component
Kinetochore
Chromatin
Nucleosome
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Brush Border
Cell-cell Junction
Adherens Junction
Focal Adhesion
Actin Cytoskeleton
Membrane
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Lamellipodium
Axon
Cortical Cytoskeleton
Vesicle
Protein-containing Complex
Brahma Complex
NuA4 Histone Acetyltransferase Complex
Cytoplasmic Ribonucleoprotein Granule
Apical Junction Complex
Calyx Of Held
Synapse
Extracellular Exosome
Tight Junction
NpBAF Complex
NBAF Complex
Blood Microparticle
Dense Body
Schaffer Collateral - CA1 Synapse
Presynapse
Postsynaptic Actin Cytoskeleton
Glutamatergic Synapse
BBAF Complex
GBAF Complex
Ribonucleoprotein Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Postsynaptic Density
Synapse
Glutamatergic Synapse
MCRD-mediated MRNA Stability Complex
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Kinesin Binding
Protein Kinase Binding
Nitric-oxide Synthase Regulator Activity
Tat Protein Binding
Nucleosomal DNA Binding
Identical Protein Binding
Tau Protein Binding
Nitric-oxide Synthase Binding
Structural Constituent Of Postsynaptic Actin Cytoskeleton
Transporter Regulator Activity
Nucleic Acid Binding
DNA Binding
Minor Groove Of Adenine-thymine-rich DNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Telomeric DNA Binding
Histone Deacetylase Binding
Biological Process
Morphogenesis Of A Polarized Epithelium
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Cytoskeleton Organization
Establishment Or Maintenance Of Cell Polarity
Axonogenesis
Positive Regulation Of Cell Population Proliferation
Substantia Nigra Development
Regulation Of Mitotic Metaphase/anaphase Transition
Adherens Junction Assembly
Maintenance Of Blood-brain Barrier
Regulation Of Apoptotic Process
Apical Protein Localization
Positive Regulation Of T Cell Differentiation
Negative Regulation Of Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of DNA-templated Transcription
Cell Motility
Regulation Of Norepinephrine Uptake
Positive Regulation Of Norepinephrine Uptake
Regulation Of Cell Cycle
Regulation Of G0 To G1 Transition
Platelet Aggregation
Protein Localization To Adherens Junction
Cellular Response To Cytochalasin B
Postsynaptic Actin Cytoskeleton Organization
Regulation Of Transepithelial Transport
Regulation Of Synaptic Vesicle Endocytosis
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Double-strand Break Repair
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Liver Development
Regulation Of DNA-templated Transcription
RNA Processing
RNA Catabolic Process
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Cerebellum Development
Positive Regulation Of Telomere Maintenance Via Telomerase
Response To Estradiol
Regulation Of Circadian Rhythm
Regulation Of MRNA Stability
Positive Regulation Of Translation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Response To Calcium Ion
Response To Electrical Stimulus
3'-UTR-mediated MRNA Destabilization
CRD-mediated MRNA Stabilization
Cellular Response To Amino Acid Stimulus
Cellular Response To Estradiol Stimulus
Cellular Response To Nitric Oxide
Circadian Regulation Of Translation
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Response To Rapamycin
Positive Regulation Of Telomere Capping
Response To Sodium Phosphate
Cellular Response To Putrescine
Hepatocyte Dedifferentiation
Positive Regulation Of Cytoplasmic Translation
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Gap junction degradation
Formation of annular gap junctions
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
HATs acetylate histones
Prefoldin mediated transfer of substrate to CCT/TriC
Folding of actin by CCT/TriC
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
Adherens junctions interactions
Adherens junctions interactions
Recycling pathway of L1
Recycling pathway of L1
VEGFA-VEGFR2 Pathway
Interaction between L1 and Ankyrins
Interaction between L1 and Ankyrins
Cell-extracellular matrix interactions
B-WICH complex positively regulates rRNA expression
RHO GTPases activate IQGAPs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
RHO GTPases Activate Formins
MAP2K and MAPK activation
UCH proteinases
DNA Damage Recognition in GG-NER
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Clathrin-mediated endocytosis
RHOF GTPase cycle
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of CDH1 Function
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Factors involved in megakaryocyte development and platelet production
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of the non-canonical BAF (ncBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Quercetin
Phenethyl Isothiocyanate
Artenimol
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Global electrical heterogeneity phenotypes (
29622589
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Lymphocyte count (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
32888494
)
Relative hand skill in reading disability (
24068947
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Triglyceride levels (
32203549
)
Chronotype (
30696823
)
Coronary artery disease (
32469254
33020668
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Morning person (
30696823
)
Refractive error (
32231278
)
Interacting Genes
161 interacting genes:
A2M
ABLIM1
ABRA
ACD
ACTC1
ACTG1
ALOX5
ANXA7
AQP2
AR
ARPC1B
ATF7IP
BBS4
BCL2L1
CAP1
CAPZA1
CCN2
CCT2
CCT4
CCT5
CCT8
CDC37
CDK5R2
CDKN1A
CDKN2A
CFL1
CFL2
CLIC4
CLIC6
CLNS1A
CNN2
CORO1A
CORO7
COTL1
CPNE1
CPNE2
CPNE4
CREBBP
CSNK1A1
CSNK2B
DMTN
DNASE1
DSCR9
DSTN
DUSP19
DYNLL1
EEF1A1
EHHADH
EMD
ERG
EZR
FABP4
FHL3
FLII
FXR1
GAPDH
GNA12
GSN
H2AX
HCK
HIP1R
HMMR
HNRNPAB
HNRNPD
HNRNPU
HSD17B4
HSPB2
HTR6
KHDRBS1
LASP1
LCOR
LGALS13
LINC01554
LINC02582
LMNA
LMOD1
LRRK2
LYN
MAP1B
MAP2
MAPT
MRGBP
MTNR1A
MX1
MYO18B
MYO1E
MYOC
NCALD
NCF1
NDEL1
NEBL
NOS2
NRAP
NSMAF
NT5E
NTAQ1
OGT
P2RX7
PCYT1A
PDIA2
PDLIM5
PFDN1
PFDN4
PFN1
PFN2
PHACTR4
PLD1
PLD2
PLG
POLR2A
POT1
PRKCD
PROSER2
PTN
PTPRF
RAB4A
RAC1
RAC2
RCC1
RPL10A
S100A11
SAMHD1
SCN10A
SHBG
SMAD3
SMAD9
SMARCA4
SMN1
SPTAN1
SPTB
SPTBN2
SRPK2
SSH1
SSH2
SSH3
STX4
SUMO2
SYNJ2BP
TANC1
TGM2
TINF2
TK1
TMSB4X
TMSB4XP1
TMSB4XP4
TNNI2
TPM1
TPM2
TPM3
TRIM15
TSHR
TTR
UBC
UBE2I
UBE3A
VHL
VSNL1
WASF1
WASF2
WASF3
XPO6
98 interacting genes:
ABCC10
ACTB
ADGRE5
ARF4
B3GAT3
BET1L
BRCA1
C1QBP
CAPN1
CD81
CEBPA
CINP
COG7
COL18A1
CSDE1
CTSB
CUTA
DGCR2
DHX30
DMAC1
EEF2
ERG
ESR1
EXOSC4
FBXL15
FILNC1
FLNA
FNDC3B
FOS
FOXP1
GSK3B
GTF3C3
GTSE1
GUK1
HBZ
HDAC1
HIRA
HMGA1
HNRNPH3
HSPA4
HSPB1
HSPB2
IGF2BP2
IL6
IL7R
IMMP2L
IMMT
ING4
LDHA
LINC01232
LSM5
MAP2K1
MAPK6
MEOX2
MPP1
MTA2
MYC
NEDD4L
NTMT1
OGT
P4HB
PABPC1
PCBP1
PCBP2
PCSK7
PDLIM7
PEX10
PPOX
PRDX3
PRKACA
PTBP2
PYCR1
RALY
RPSA
SAFB
SDF2
SEPTIN9
SF3B4
SFN
SHISA5
SLC27A5
SLC3A2
SNAPC4
SREK1
SUMO4
SYNCRIP
TNF
TNPO1
TOP2A
TRN-GTT2-7
TSEN34
UBE2I
UCP3
UQCRC1
VEGFA
VHL
YBX1
ZMYM4
Entrez ID
60
3184
HPRD ID
00032
03206
Ensembl ID
ENSG00000075624
ENSG00000138668
Uniprot IDs
P60709
Q1KLZ0
Q14103
PDB IDs
3BYH
3D2U
3J82
3LUE
6ANU
6ICT
6ICV
6LTJ
6MBJ
6MBK
6MBL
6NBW
6OX0
6OX1
6OX2
6OX3
6OX4
6OX5
6V62
6V63
6WK1
6WK2
7AS4
7P1H
7QJ6
7QJ9
7VDV
7W28
7W29
7Y8R
7ZTC
7ZTD
8COG
8DNH
8IB8
8OI8
8OID
8QR1
8RTT
8RTY
8RU2
8RX1
8UAU
8VRD
8VRJ
8VRK
8X15
8X19
8X1C
8XVG
8XVT
9B2Z
9C57
9C62
9C6N
9FJM
1HD0
1HD1
1IQT
1WTB
1X0F
2Z5N
5IM0
Enriched GO Terms of Interacting Partners
?
Actin Binding
Regulation Of Cytoskeleton Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Organization
Regulation Of Actin Filament-based Process
Regulation Of Organelle Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Negative Regulation Of Supramolecular Fiber Organization
Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Actin Filament-based Process
Actin Filament Binding
Regulation Of Cellular Component Organization
Regulation Of Cellular Component Size
Actin Filament Organization
Negative Regulation Of Cytoskeleton Organization
Cytoskeleton
Negative Regulation Of Actin Filament Polymerization
Cytoplasm
Negative Regulation Of Cellular Component Organization
Cytoskeleton Organization
Supramolecular Fiber Organization
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Organelle Organization
Actin Cytoskeleton
Regulation Of Biological Quality
Negative Regulation Of Protein-containing Complex Assembly
Extracellular Exosome
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Supramolecular Fiber Organization
Cortical Actin Cytoskeleton
Regulation Of Actin Filament Depolymerization
Actin Filament
Organelle Organization
Glutamatergic Synapse
Positive Regulation Of Cellular Component Organization
Modification Of Postsynaptic Actin Cytoskeleton
Cytosol
Regulation Of Protein Localization
Regulation Of Protein Depolymerization
Negative Regulation Of Actin Filament Depolymerization
Focal Adhesion
Regulation Of Telomere Maintenance Via Telomerase
Modification Of Postsynaptic Structure
Actin Filament Capping
Postsynapse
Modification Of Synaptic Structure
Regulation Of Cellular Localization
RNA Binding
CRD-mediated MRNA Stabilization
Macromolecule Metabolic Process
Positive Regulation Of Translation
Ribonucleoprotein Complex
Positive Regulation Of Cytoplasmic Translation
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression
MRNA Metabolic Process
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of Programmed Cell Death
RNA Metabolic Process
Nucleic Acid Binding
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Response To Stress
Negative Regulation Of Apoptotic Process
Cellular Response To Stress
Regulation Of Cytoplasmic Translation
MCRD-mediated MRNA Stability Complex
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
CRD-mediated MRNA Stability Complex
Positive Regulation Of Gene Expression
Transcription Coregulator Binding
Regulation Of Gene Expression
Regulation Of Translation
Nucleic Acid Metabolic Process
Regulation Of MiRNA Transcription
Focal Adhesion
Negative Regulation Of Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
RNA Splicing
Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
MRNA Processing
Regulation Of Macromolecule Biosynthetic Process
Spliceosomal Complex
Nucleoplasm
Negative Regulation Of Catabolic Process
Regulation Of DNA-templated Transcription
Regulation Of MiRNA Metabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?