EEF1A1 and PTPRCAP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1A1	PTPRCAP
Gene Name		eukaryotic translation elongation factor 1 alpha 1	protein tyrosine phosphatase, receptor type, C-associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus	Defense Response
Pathways		HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	2 interactors: EEF1A1 PTPRC
Entrez ID		1915	5790
HPRD ID		00559	09032
Ensembl ID		ENSG00000156508
Uniprot IDs		P68104 Q6IPS9	Q14761
PDB IDs		1SYW
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity	Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Negative Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Isotype Switching To IgG Isotypes Bone Marrow Development Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Gamma-delta T Cell Differentiation Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Positive Thymic T Cell Selection Positive Regulation Of Gamma-delta T Cell Activation Negative Regulation Of Protein Autophosphorylation Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of T Cell Mediated Immunity Negative Thymic T Cell Selection Positive Regulation Of Alpha-beta T Cell Proliferation Negative T Cell Selection Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Humoral Immune Response Heterotypic Cell-cell Adhesion Thymic T Cell Selection Positive Regulation Of Isotype Switching Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Positive T Cell Selection Response To Epidermal Growth Factor Regulation Of Protein Autophosphorylation Regulation Of B Cell Differentiation Regulation Of Isotype Switching Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Immunoglobulin Mediated Immune Response Negative Regulation Of Adaptive Immune Response Substrate-dependent Cell Migration Negative Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Immunoglobulin Production B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Negative Regulation Of Response To Cytokine Stimulus B Cell Proliferation T Cell Selection Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Humoral Immune Response Response To Gamma Radiation Regulation Of B Cell Proliferation Immunoglobulin Production Regulation Of DNA Recombination T Cell Differentiation In Thymus
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	agtrl2 biased bioinformatic chrna5 ctsg cyp2d6 dld ercc1 gabra1 gabrp heritable hip1 hnrph3 igkv1 il24 impossible kcnj15 kcnk6 klk1 msmb myoc nonfunctional notch4 npy2r orm2 pedf st16 sult1a1 unfortunately
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	agtrl2 biased bioinformatic chrna5 ctsg cyp2d6 dld ercc1 gabra1 gabrp heritable hip1 hnrph3 igkv1 il24 impossible kcnj15 kcnk6 klk1 msmb myoc nonfunctional notch4 npy2r orm2 pedf st16 sult1a1 unfortunately
Tagcloud (Intersection) ?