EEF1A1 and PAPSS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1A1	PAPSS1
Description		eukaryotic translation elongation factor 1 alpha 1	3'-phosphoadenosine 5'-phosphosulfate synthase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Ribosome Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Cytosolic Ribosome Cortical Actin Cytoskeleton Ruffle Membrane Secretory Granule Lumen Extracellular Exosome Cytoplasmic Side Of Lysosomal Membrane Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Cytosol
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity Kinase Activator Activity Kinase Binding Protein Kinase Binding Molecular Adaptor Activity	Nucleotide Binding Catalytic Activity Adenylylsulfate Kinase Activity Sulfate Adenylyltransferase (ATP) Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity Protein Homodimerization Activity
	Biological Process	Translation Translational Elongation Host-mediated Activation Of Viral Genome Replication Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Chaperone-mediated Autophagy	Sulfate Assimilation Skeletal System Development 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process
Pathways		Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy SARS-CoV-1 modulates host translation machinery	Transport and metabolism of PAPS Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Signaling by BRAF and RAF1 fusions
Drugs		Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Adenosine-5'-diphosphate-2',3'-vanadate Adenosine 5'-phosphosulfate Glycerin
Diseases
GWAS			Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Telomere length ( 24478790)
Interacting Genes		144 interacting genes: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 AQP2 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCL18 CDC25A CDKN1A CEBPA CKS2 CLIC6 COX17 CRADD CRCT1 CREBBP CSRP2 CTIF DARS1 DCTN1 DIABLO DLEU1 DNMT1 DNMT3A DUSP7 DYNLL1 DYSF EIF3F EP300 EXOSC4 FAS GADD45A GADD45G HOXA1 HSPB2 HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP OGT ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP PTPRF RAB27A RAP2A RFC5 RGS12 RND1 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB5 SERPINB9 SF3B4 SFN SHBG SMAD2 SMAD4 SMN1 SPATS2L SPP1 SSR1 STAT6 STMN2 SULT1E1 SUMO2 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSC2 TSPY1 TSPYL2 TTLL12 TTR TXNIP UBQLN4 USP40 VHL WARS1 WEE2-AS1 XPO5 XRN2 YJU2B YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	4 interacting genes: EEF1A1 ERRFI1 PPP1R16A UNC119
Entrez ID		1915	9061
HPRD ID		00559	09132
Ensembl ID		ENSG00000156508	ENSG00000138801
Uniprot IDs		P68104 Q6IPS9	O43252
PDB IDs		3C5J 6ZMO 8G60 8G6J	1X6V 1XJQ 1XNJ 2OFW 2OFX 2PEY 2PEZ 2QJF 8I1M
Enriched GO Terms of Interacting Partners?		Cytoplasm Apoptotic Process Cell Death Programmed Cell Death Regulation Of Programmed Cell Death Cytosol Negative Regulation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Nucleic Acid Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Apoptotic Signaling Pathway BBSome Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling TORC1 Signaling Protein-containing Complex Nucleus Macromolecule Biosynthetic Process Melanosome Transport Tau Protein Binding Regulation Of Developmental Process RNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Establishment Of Melanosome Localization Pigment Granule Transport Negative Regulation Of Protein Phosphorylation Cellular Response To Stress Melanosome Localization Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Macromolecule Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pigment Granule Localization Mitochondrial Intermembrane Space Nucleoplasm Protein Binding Negative Regulation Of Catalytic Activity Histone H3K27 Acetyltransferase Activity Negative Regulation Of Phosphate Metabolic Process TOR Signaling Positive Regulation Of TOR Signaling Regulation Of Phosphorus Metabolic Process	Regulation Of Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Peptidyl-tyrosine Phosphorylation U6 2'-O-snRNA Methylation Kinase Binding Negative Regulation Of Caveolin-mediated Endocytosis Uterine Epithelium Development Response To 1-oleoyl-sn-glycerol 3-phosphate Eukaryotic Translation Elongation Factor 1 Complex Negative Regulation Of Clathrin-dependent Endocytosis Box C/D Sno(s)RNA 3'-end Processing Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP Negative Regulation Of Protein Autophosphorylation Oviduct Epithelium Development Response To Growth Factor Cellular Response To Growth Factor Stimulus Kinase Activator Activity Host-mediated Perturbation Of Viral Genome Replication Cytoplasmic Side Of Lysosomal Membrane Host-mediated Activation Of Viral Genome Replication Regulation Of Chaperone-mediated Autophagy Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Tyrosine Kinase Activity SnRNA Modification 7SK SnRNA Binding Positive Regulation Of Protein Localization To Cajal Body U6 SnRNA Binding Skin Morphogenesis Negative Regulation Of Signaling Receptor Activity Lung Vasculature Development Limb Joint Morphogenesis Fat Pad Development Progesterone Receptor Signaling Pathway Regulation Of Type B Pancreatic Cell Proliferation Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Myosin Phosphatase Regulator Activity Chondrocyte Proliferation Lung Epithelium Development Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Viral Transcription Translation Elongation Factor Activity Lipoprotein Transport Regulation Of Protein Phosphorylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?