EEF1A1 and LAMTOR5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1A1	LAMTOR5
Gene Name		eukaryotic translation elongation factor 1 alpha 1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome	Lysosome Cytosol Ragulator Complex
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus	Regulation Of Cell Size Response To Virus Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	16 interactors: CEP70 EEF1A1 GAPDH GIT1 GPRASP1 KIAA1377 LAMTOR4 LRIF1 MAF1 MEOX2 NCOA6 RABIF TAF9 UTP14A YTHDC1 ZBTB16
Entrez ID		1915	10542
HPRD ID		00559	09773
Ensembl ID		ENSG00000156508	ENSG00000134248
Uniprot IDs		P68104 Q6IPS9	O43504
PDB IDs		1SYW	3MS6 3MSH
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Factor TFIIIB Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Gene Expression Neuron Death Nucleobase-containing Compound Metabolic Process G-protein Coupled Receptor Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Embryonic Pattern Specification Protein Stabilization Negative Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Stability Male Germ-line Stem Cell Asymmetric Division Somite Specification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Glucocorticoid Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Macromolecule Biosynthetic Process
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?