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TRA2B and NGFR
Number of citations of the paper that reports this interaction (PubMedID
12604596
)
0
Data Source:
HPRD
(in vivo)
TRA2B
NGFR
Description
transformer 2 beta homolog
nerve growth factor receptor
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Inner Membrane
Nucleoplasm
Spliceosomal Complex
Protein-containing Complex
Extracellular Region
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Plasma Membrane
Cell-cell Junction
Cell Surface
Postsynaptic Density
Membrane
Growth Cone
Neuromuscular Junction
Cell Projection
Dendritic Spine
Perikaryon
Organelle
Synapse
Presynapse
Molecular Function
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Protein Domain Specific Binding
Pre-mRNA Binding
Identical Protein Binding
Amyloid-beta Binding
Transmembrane Signaling Receptor Activity
Death Receptor Activity
Protein Binding
Calmodulin Binding
Coreceptor Activity
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
Neurotrophin Binding
Nerve Growth Factor Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Cerebral Cortex Regionalization
Regulation Of RNA Splicing
Positive Regulation Of MRNA Splicing, Via Spliceosome
Cellular Response To Glucose Stimulus
Embryonic Brain Development
Intracellular Glucose Homeostasis
Hair Follicle Development
Intracellular Protein Transport
Apoptotic Process
Signal Transduction
Rho Protein Signal Transduction
Nervous System Development
Axon Guidance
Central Nervous System Development
Circadian Rhythm
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Gene Expression
Detection Of Temperature Stimulus
Nerve Development
Cell Differentiation
Negative Regulation Of Cell Migration
Hair Follicle Morphogenesis
Circadian Regulation Of Gene Expression
Dorsal Aorta Development
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Odontogenesis Of Dentin-containing Tooth
Positive Regulation Of Odontogenesis Of Dentin-containing Tooth
Glucose Homeostasis
Positive Regulation Of Apoptotic Process
Skin Development
Fibroblast Proliferation
Positive Regulation Of Fibroblast Proliferation
Rhythmic Process
Neuron Apoptotic Process
Negative Regulation Of Hair Follicle Development
Extrinsic Apoptotic Signaling Pathway
Presynaptic Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of MiRNA Transcription
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Cellular Response To Amyloid-beta
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
RHOBTB2 GTPase cycle
RHOBTB1 GTPase cycle
Axonal growth inhibition (RHOA activation)
NRAGE signals death through JNK
p75NTR negatively regulates cell cycle via SC1
Ceramide signalling
Regulated proteolysis of p75NTR
NFG and proNGF binds to p75NTR
NADE modulates death signalling
NRIF signals cell death from the nucleus
NRIF signals cell death from the nucleus
p75NTR recruits signalling complexes
p75NTR recruits signalling complexes
NF-kB is activated and signals survival
Axonal growth stimulation
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Height (
31562340
)
Menarche (age at onset) (
21102462
25231870
27182965
)
Post bronchodilator FEV1 (
26634245
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Immune reponse to smallpox (secreted IL-2) (
22610502
)
Lower body strength (
27325353
)
Mean spheric corpuscular volume (
32888494
)
Prostate cancer (
23535732
)
Interacting Genes
107 interacting genes:
-
CDK6
CLK1
CLK3
EPM2AIP1
HINFP
HIPK3
HNRNPA1
IVNS1ABP
LUM
MAGOHB
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYPOP
NGFR
NXF1
PCDHB14
RBMX
RBMXL2
RBMY1A1
RBMY1F
RBMY1J
RNPS1
SREK1
SRPK1
SRSF10
SRSF2
SRSF3
SRSF4
SRSF8
SRSF9
TNPO3
U2AF1
YTHDC1
YWHAG
YWHAZ
ZRANB2
50 interacting genes:
ANXA7
APP
BEX1
BEX3
BNIP3L
CAV1
CD80
CDKN1A
EGR1
FSCN1
GRB2
H2AX
IL2
KIDINS220
LINGO1
MAG
MAGED1
MAGEH1
MAPK1
MAPK3
MDM2
NDN
NFKBIB
NGF
NSMCE3
NTF4
NTRK1
NTRK2
NTRK3
PRKACB
PTPN13
RCC1
RIPK2
RPN2
RTN4R
SHC1
SMN1
SORT1
STMN2
TK1
TP53
TRA2B
TRADD
TRAF2
TRAF4
TRAF6
TRIM37
TTR
UFD1
ZNF274
Entrez ID
6434
4804
HPRD ID
04097
01197
Ensembl ID
ENSG00000136527
ENSG00000064300
Uniprot IDs
P62995
P08138
PDB IDs
2CQC
2KXN
2RRA
2RRB
2N80
2N83
2N97
3EWV
5ZGG
7CSQ
8X8T
Enriched GO Terms of Interacting Partners
?
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Extracellular Vesicle
Regulation Of Macromolecule Metabolic Process
Regulation Of MRNA Metabolic Process
Negative Regulation Of Translation
Regulation Of Metabolic Process
Positive Regulation Of MRNA Metabolic Process
MRNA Destabilization
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Cell Motility
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Negative Regulation Of Locomotion
Negative Regulation Of Cytokine Production
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Regulation Of Translation
Regulation Of MRNA Stability
Regulation Of RNA Stability
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Multicellular Organismal Process
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Developmental Process
Regulation Of Endothelial Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Extracellular Space
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of Programmed Cell Death
Nerve Growth Factor Signaling Pathway
Regulation Of Apoptotic Process
Response To Growth Factor
Signal Transduction
Response To Nerve Growth Factor
Regulation Of Protein Metabolic Process
Protein-containing Complex
Cellular Response To Nerve Growth Factor Stimulus
Regulation Of Protein Modification Process
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of MAPK Cascade
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Intracellular Signal Transduction
Enzyme Binding
Apoptotic Process
Regulation Of Multicellular Organismal Process
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Programmed Cell Death
Cell Death
Identical Protein Binding
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of MAPK Cascade
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Receptor Activity
Neurotrophin Binding
Positive Regulation Of Macromolecule Metabolic Process
Cellular Response To Growth Factor Stimulus
Signaling Adaptor Activity
Regulation Of Gene Expression
Regulation Of Cellular Component Organization
Circadian Rhythm
Regulation Of Macromolecule Biosynthetic Process
Caveolin-mediated Endocytosis
Nerve Growth Factor Receptor Binding
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Signal Transduction
Cytokine-mediated Signaling Pathway
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Myelination
Apoptotic Signaling Pathway
Axon Ensheathment
Regulation Of Cell Projection Organization
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
Response To Radiation
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