SF3A3 and WBP4

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		SF3A3	WBP4
Gene Name		splicing factor 3a, subunit 3, 60kDa	WW domain binding protein 4
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	MRNA Cis Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		16 interactors: ADAP1 APBB1 APP CCDC85B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212	44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		10946	11193
HPRD ID		10411	16086
Ensembl ID		ENSG00000183431	ENSG00000120688
Uniprot IDs		B3KY12 E7EUT8 Q12874	B7Z4M2 O75554
PDB IDs		2DT7	2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing RNA Splicing Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Visual Learning Visual Behavior Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA 3'-end Processing Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Synaptic Growth At Neuromuscular Junction Associative Learning Axon Guidance Collateral Sprouting In Absence Of Injury Histone Modification RNA 3'-end Processing Histone Acetylation Regulation Of Cell Cycle Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Tubulin Deacetylation MRNA 3'-splice Site Recognition Protein Acetylation Programmed Cell Death Learning Regulation Of Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Death Death Axon Choice Point Recognition Negative Regulation Of Cell Growth Axonogenesis Regulation Of Transcription From RNA Polymerase II Promoter	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress
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