SF3A3 and TCERG1

Number of citations of the paper that reports this interaction (PubMedID 15456888)
53

Data Source:
HPRD (in vitro)

		SF3A3	TCERG1
Description		splicing factor 3a subunit 3	transcription elongation regulator 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Elongation Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Appendicular lean mass ( 33097823) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 28869591 30598549) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		38 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MIR106B MIR107 MIR141 MIR145 MIR155 MIR199A1 MIR200A MIR200C MIR206 MIR214 MIR221 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MTNR1B OGT PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212	56 interacting genes: ABI1 AURKA BARD1 CEBPA CHAF1A CHD3 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 RNF10 RUNX1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO2 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		10946	10915
HPRD ID		10411	10393
Ensembl ID		ENSG00000183431	ENSG00000113649
Uniprot IDs		B4DW90 Q12874	A0A7P0T8N8 O14776
PDB IDs		2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y50 6Y53 6Y5Q 7ABG 7ABH 7ABI 7EVO 7ONB 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5	2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG 7ABF 7ABG 8Q7N 8QO9
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Negative Regulation Of Translation Extracellular Vesicle Regulation Of Translation Regulation Of Angiogenesis Negative Regulation Of Cell Migration MRNA Destabilization Regulation Of Vasculature Development Negative Regulation Of Cytokine Production RNA Destabilization Negative Regulation Of Cell Motility Regulation Of Gene Expression Negative Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Signal Transduction Regulation Of Connective Tissue Replacement Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Cytokine Production Positive Regulation Of Tissue Remodeling Regulation Of Macromolecule Metabolic Process Regulation Of Cell Motility Regulation Of MRNA Stability Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Programmed Cell Death Regulation Of Locomotion Negative Regulation Of Transport Regulation Of RNA Stability Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex RNA Splicing MRNA Processing MRNA Metabolic Process RNA Binding Catalytic Step 2 Spliceosome Spliceosomal Complex Assembly Nucleic Acid Metabolic Process Nuclear Speck Nucleoplasm U2-type Prespliceosome Assembly Nucleus Nucleic Acid Binding U2 SnRNP RNA Metabolic Process Nucleobase-containing Compound Metabolic Process U2-type Spliceosomal Complex U2-type Precatalytic Spliceosome RNA Processing Protein-containing Complex Assembly Protein-containing Complex Organization Protein-RNA Complex Assembly Paraspeckles Cellular Component Assembly MRNA Splice Site Recognition MRNA 3'-splice Site Recognition U2-type Prespliceosome Regulation Of RNA Splicing SCAR Complex Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Nuclear Matrix Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Actin Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Actin Polymerization Or Depolymerization Alternative MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex MRNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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