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WBP4 and DNM2
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
WBP4
DNM2
Gene Name
WW domain binding protein 4
dynamin 2
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Plasma Membrane
Nuclear Speck
Golgi Membrane
Cytoplasm
Golgi Apparatus
Cytosol
Microtubule
Plasma Membrane
Coated Pit
Focal Adhesion
Postsynaptic Density
Growth Cone
Midbody
Endocytic Vesicle Membrane
Postsynaptic Membrane
Extracellular Vesicular Exosome
Molecular Function
Nucleic Acid Binding
Protein Binding
Zinc Ion Binding
Proline-rich Region Binding
GTPase Activity
Protein Binding
GTP Binding
Microtubule Binding
SH3 Domain Binding
Enzyme Binding
Biological Process
MRNA Cis Splicing, Via Spliceosome
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Transcription, DNA-templated
Post-Golgi Vesicle-mediated Transport
Endocytosis
Receptor-mediated Endocytosis
Signal Transduction
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Regulation Of Axon Extension
Receptor Internalization
Transferrin Transport
Positive Regulation Of Apoptotic Process
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Nitric Oxide Metabolic Process
Synaptic Vesicle Transport
Neuron Projection Morphogenesis
Regulation Of Nitric-oxide Synthase Activity
Membrane Organization
Negative Regulation Of Membrane Tubulation
Pathways
Retrograde neurotrophin signalling
Axon guidance
Gap junction degradation
Golgi Associated Vesicle Biogenesis
L1CAM interactions
Recycling pathway of L1
Clathrin derived vesicle budding
Lysosome Vesicle Biogenesis
Metabolism of nitric oxide
Gap junction trafficking and regulation
NOSTRIN mediated eNOS trafficking
MHC class II antigen presentation
eNOS activation and regulation
trans-Golgi Network Vesicle Budding
Innate Immune System
Formation of annular gap junctions
Signalling by NGF
Gap junction trafficking
NGF signalling via TRKA from the plasma membrane
Toll-Like Receptors Cascades
Toll Like Receptor 4 (TLR4) Cascade
Adaptive Immune System
Drugs
Diseases
GWAS
Crohn's disease (
23266558
)
Coronary heart disease (
21347282
)
Protein-Protein Interactions
44 interactors:
BUB3
CAPRIN1
CHERP
CHTF8
CPSF6
CPSF7
DDX23
DDX3X
DHX15
DIAPH1
DNM2
EFTUD2
EWSR1
FUS
HLTF
HNRNPK
HNRNPU
HTATSF1
KHDRBS1
NONO
PABPC1
PRPF3
PRPF4
PRPF40A
PSPC1
SART1
SCAF4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B3
SF3B4
SFPQ
SNRNP70
SNRPA
SNRPB
TCERG1
WAS
WBP11
WIPF1
XRCC6
ZNF207
52 interactors:
AMPH
AOC1
AP2A1
APP
ATF7IP
ATXN3
BIN1
CCDC90B
CCR5
CCT7
CDK1
CTTN
DDX39B
DNM1
DYNC1I1
DYNLL1
EIF3L
EPS15
FNBP1
FNBP1L
GDF9
GRB2
HCK
HMGB1
ITSN1
ITSN2
KDR
MAN1B1
MANEA
MPHOSPH6
MPP6
PDE6G
PFN1
PPIB
PSTPIP1
PTK2
RPS2
RWDD2B
SH3GL2
SH3GLB1
SHANK1
SHANK2
SNX9
SPRY2
SRC
TIAM2
TRIP10
TYK2
VAV1
WBP4
ZBTB16
ZFAND6
Entrez ID
11193
1785
HPRD ID
16086
03852
Ensembl ID
ENSG00000120688
ENSG00000079805
Uniprot IDs
B7Z4M2
O75554
P50570
Q8N1K8
PDB IDs
2DK1
2JXW
2YS1
Enriched GO Terms of Interacting Partners
?
MRNA Processing
RNA Splicing
RNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
MRNA 3'-splice Site Recognition
Ribonucleoprotein Complex Biogenesis
Cellular Metabolic Process
Cellular Macromolecular Complex Assembly
Spliceosomal Complex Assembly
Cellular Component Assembly
MRNA Splice Site Selection
Cellular Process
Metabolic Process
MRNA 3'-end Processing
Transcription, DNA-templated
RNA Biosynthetic Process
RNA 3'-end Processing
Spliceosomal SnRNP Assembly
Posttranscriptional Regulation Of Gene Expression
Attachment Of Spindle Microtubules To Kinetochore
Rhythmic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of Translational Initiation
Macromolecule Biosynthetic Process
Positive Regulation Of Translation
Actin Polymerization Or Depolymerization
Negative Regulation Of Gene Expression
MRNA Cis Splicing, Via Spliceosome
Negative Regulation Of Biosynthetic Process
Regulation Of MRNA Processing
Regulation Of Circadian Rhythm
Regulation Of RNA Metabolic Process
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of MRNA Splicing, Via Spliceosome
MRNA Stabilization
Positive Regulation Of Gene Expression
MRNA Polyadenylation
Cellular Response To Osmotic Stress
Endocytosis
Vesicle-mediated Transport
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cellular Response To Growth Factor Stimulus
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Response To Growth Factor
Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Locomotion
Cellular Response To Organic Substance
Chemotaxis
Cellular Localization
Regulation Of Signal Transduction
Regulation Of Signaling
Transport
Neurotrophin TRK Receptor Signaling Pathway
Viral Process
Positive Regulation Of Cellular Component Biogenesis
Peptidyl-tyrosine Autophosphorylation
Neurotrophin Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Protein Complex Assembly
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Establishment Of Localization In Cell
Regulation Of Cell Death
Negative Regulation Of ERBB Signaling Pathway
Neuron Projection Morphogenesis
Positive Regulation Of Protein Complex Assembly
Neuron Projection Development
Axon Guidance
Cell Projection Morphogenesis
Cell Part Morphogenesis
Regulation Of Cellular Component Organization
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Catalytic Activity
Response To Organic Substance
Nervous System Development
Neuron Development
Cell Projection Organization
Response To External Stimulus
Apoptotic Process
Cellular Component Assembly
Programmed Cell Death
Cell Migration
Immune System Process
Axonogenesis
Cell Death
Tagcloud
?
bcl11b
cadherin
discovered
druggable
exhibitedthe
fat1
fbxw7
frequencies
guide
harboured
herc1
jak
jak3
lymphoblastic
mll2
mutational
notch1
notch2
phf6
recurrent
regulators
reln
secretase
splicing
subclonal
unfavourable
warranted
wt1
zrsr2
Tagcloud (Difference)
?
bcl11b
cadherin
discovered
druggable
exhibitedthe
fat1
fbxw7
frequencies
guide
harboured
herc1
jak
jak3
lymphoblastic
mll2
mutational
notch1
notch2
phf6
recurrent
regulators
reln
secretase
splicing
subclonal
unfavourable
warranted
wt1
zrsr2
Tagcloud (Intersection)
?