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SF3A3 and VAV2
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
SF3A3
VAV2
Gene Name
splicing factor 3a, subunit 3, 60kDa
vav 2 guanine nucleotide exchange factor
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
Catalytic Step 2 Spliceosome
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Zinc Ion Binding
Poly(A) RNA Binding
Guanyl-nucleotide Exchange Factor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
MRNA 3'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Angiogenesis
Signal Transduction
Small GTPase Mediated Signal Transduction
Axon Guidance
Blood Coagulation
Regulation Of Gene Expression
Cell Migration
Lamellipodium Assembly
Platelet Activation
Regulation Of Blood Coagulation
Positive Regulation Of Rho GTPase Activity
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Apoptotic Process
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Innate Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Apoptotic Signaling Pathway
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Signaling by GPCR
Axon guidance
L1CAM interactions
FCERI mediated MAPK activation
VEGFA-VEGFR2 Pathway
Rho GTPase cycle
DAP12 signaling
EPH-ephrin mediated repulsion of cells
VEGFR2 mediated vascular permeability
EPH-Ephrin signaling
G alpha (12/13) signalling events
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Signalling by NGF
DAP12 interactions
Signal transduction by L1
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
GPCR downstream signaling
Signaling by VEGF
NRAGE signals death through JNK
Signaling by Rho GTPases
GPVI-mediated activation cascade
Fc epsilon receptor (FCERI) signaling
FCERI mediated Ca+2 mobilization
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Multiple sclerosis (
20598377
)
vWF and FVIII levels (
21810271
)
Protein-Protein Interactions
16 interactors:
ADAP1
APBB1
APP
CCDC85B
PRMT5
PRPF40A
SF3A1
SREK1
TADA2A
TCERG1
TRIM69
U2AF1
VAV2
WBP4
ZDHHC17
ZNF212
62 interactors:
ARIH1
BIRC6
BOD1L1
BRDT
BZW1
CBL
CBLB
CCNO
CCT2
CCT3
CD19
CD44
CEP170
CHMP3
CRCP
DCUN1D4
DNAJC21
EGFR
EIF4G3
EPHB2
ERBB2
ERBB3
FNTA
FUCA1
FYN
GAPVD1
GRB2
HNRNPF
HSPH1
IPO4
MARCH7
MED21
MRGBP
NCKAP5
NEK3
PHF10
PNMA1
POGZ
PPM1B
PRLR
RAC1
RAD23A
RBBP6
RHOA
RHOG
SERBP1
SF3A3
SH3BP2
SNW1
SOCS1
SRPK2
SRRT
ST13
STK24
SYK
TARBP2
TCP11
TOM1L1
TTN
UBE4B
USP38
VCPIP1
Entrez ID
10946
7410
HPRD ID
10411
02694
Ensembl ID
ENSG00000183431
ENSG00000160293
Uniprot IDs
B3KY12
E7EUT8
Q12874
P52735
PDB IDs
2DT7
2DLZ
2DM1
2LNW
2LNX
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Metabolic Process
RNA Metabolic Process
RNA Processing
RNA Splicing
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Visual Learning
Visual Behavior
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
MRNA 3'-end Processing
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Synaptic Growth At Neuromuscular Junction
Associative Learning
Axon Guidance
Collateral Sprouting In Absence Of Injury
Histone Modification
RNA 3'-end Processing
Histone Acetylation
Regulation Of Cell Cycle
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Apoptotic Process
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Tubulin Deacetylation
MRNA 3'-splice Site Recognition
Protein Acetylation
Programmed Cell Death
Learning
Regulation Of Cell Cycle Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Cell Death
Death
Axon Choice Point Recognition
Negative Regulation Of Cell Growth
Axonogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Response To Fibroblast Growth Factor
Phosphatidylinositol-mediated Signaling
Cellular Response To Organic Substance
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Growth Factor
Response To Organic Substance
Peptidyl-tyrosine Phosphorylation
Fc Receptor Signaling Pathway
Platelet Activation
Innate Immune Response
Regulation Of Cellular Protein Metabolic Process
Cellular Protein Modification Process
Cellular Metabolic Process
Protein Metabolic Process
Positive Regulation Of Viral Process
Regulation Of Body Fluid Levels
Wound Healing
Immune Response
Regulation Of Cell Adhesion
Regulation Of Cell-cell Adhesion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Axon Guidance
Cell Activation
Regulation Of Signal Transduction
Response To Wounding
Regulation Of Signaling
Intracellular Signal Transduction
Regulation Of T Cell Activation
Viral Process
Positive Regulation Of Signal Transduction
Blood Coagulation
Cell Surface Receptor Signaling Pathway
Hemostasis
Protein Ubiquitination
Regulation Of Immune System Process
Signal Transduction
Regulation Of Intracellular Signal Transduction
Chemotaxis
Positive Regulation Of Homotypic Cell-cell Adhesion
Tagcloud
?
calm3
cblb
ccna2
ccnd3
cdk6
cited1
dems
dok
elk3
fyn
git1
hck
lck
module
modules
nonmodule
p85beta
pdgfra
pib5pa
psd93
ptch2
sam68
sh3kbp1
shc
tgfbr1
tgfbr2
wilcoxon
yes
zfyve9
Tagcloud (Difference)
?
calm3
cblb
ccna2
ccnd3
cdk6
cited1
dems
dok
elk3
fyn
git1
hck
lck
module
modules
nonmodule
p85beta
pdgfra
pib5pa
psd93
ptch2
sam68
sh3kbp1
shc
tgfbr1
tgfbr2
wilcoxon
yes
zfyve9
Tagcloud (Intersection)
?