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SF3A3 and APBB1
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
SF3A3
APBB1
Gene Name
splicing factor 3a, subunit 3, 60kDa
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
Catalytic Step 2 Spliceosome
Nucleus
Cytoplasm
Plasma Membrane
Nuclear Speck
Lamellipodium
Growth Cone
Synapse
Molecular Function
Protein Binding
Zinc Ion Binding
Poly(A) RNA Binding
Beta-amyloid Binding
Chromatin Binding
Protein Binding
Transcription Factor Binding
Histone Binding
Proline-rich Region Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
MRNA 3'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Neuron Migration
Double-strand Break Repair
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle Arrest
Signal Transduction
Axonogenesis
Axon Guidance
Visual Learning
Extracellular Matrix Organization
Negative Regulation Of Cell Growth
Positive Regulation Of Apoptotic Process
Histone H4 Acetylation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of DNA Repair
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
16 interactors:
ADAP1
APBB1
APP
CCDC85B
PRMT5
PRPF40A
SF3A1
SREK1
TADA2A
TCERG1
TRIM69
U2AF1
VAV2
WBP4
ZDHHC17
ZNF212
66 interactors:
ABI1
ABL1
ANXA1
APLP1
APLP2
APP
ATXN1
ATXN1L
CCDC97
CHERP
CLSTN1
CPSF6
CPSF7
CYFIP1
CYFIP2
DDX17
DDX3X
DDX46
DHX15
DHX9
DIAPH1
DIAPH2
EGFR
ENAH
ERBB2
EVL
FASLG
HNRNPH1
HNRNPK
HTATSF1
KAT5
KHDRBS1
KHSRP
LRP1
LRP2
NONO
PABPC1
PQBP1
PRNP
PTBP1
RBM17
RPL4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
TFCP2
THRAP3
TSHZ1
TSHZ2
TSHZ3
U2AF2
VASP
WAS
WASF2
WASL
WBP11
WIPF1
WIPF2
YBX1
YLPM1
Entrez ID
10946
322
HPRD ID
10411
04087
Ensembl ID
ENSG00000183431
ENSG00000166313
Uniprot IDs
B3KY12
E7EUT8
Q12874
O00213
PDB IDs
2DT7
2E45
2HO2
2IDH
2OEI
3D8D
3D8E
3D8F
3DXC
3DXD
3DXE
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Metabolic Process
RNA Metabolic Process
RNA Processing
RNA Splicing
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Visual Learning
Visual Behavior
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
MRNA 3'-end Processing
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Synaptic Growth At Neuromuscular Junction
Associative Learning
Axon Guidance
Collateral Sprouting In Absence Of Injury
Histone Modification
RNA 3'-end Processing
Histone Acetylation
Regulation Of Cell Cycle
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Apoptotic Process
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Tubulin Deacetylation
MRNA 3'-splice Site Recognition
Protein Acetylation
Programmed Cell Death
Learning
Regulation Of Cell Cycle Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Cell Death
Death
Axon Choice Point Recognition
Negative Regulation Of Cell Growth
Axonogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Processing
MRNA Processing
MRNA Metabolic Process
RNA Splicing
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Actin Polymerization Or Depolymerization
RNA Biosynthetic Process
MRNA 3'-splice Site Recognition
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Transcription, DNA-templated
Fc Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Immune Response-regulating Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Actin Filament Organization
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Component Assembly
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Phagocytosis
MRNA 3'-end Processing
Cellular Process
Regulation Of Metabolic Process
Endocytosis
Innate Immune Response
Multicellular Organismal Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of RNA Splicing
RNA 3'-end Processing
Actin Cytoskeleton Organization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Developmental Process
Actin Filament-based Process
MRNA Stabilization
Axon Guidance
Positive Regulation Of Actin Nucleation
MRNA Polyadenylation
Tagcloud
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Difference)
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Intersection)
?