WBP4 and DDX23

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	DDX23
Gene Name		WW domain binding protein 4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm U5 SnRNP Nucleolus Mitochondrion Plasma Membrane Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Poly(A) RNA Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)	Bipolar disorder ( 21926972)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	4 interactors: ERG TERF1 TERF2IP WBP4
Entrez ID		11193	9416
HPRD ID		16086	09908
Ensembl ID		ENSG00000120688	ENSG00000174243
Uniprot IDs		B7Z4M2 O75554	B3KY11 Q9BUQ8
PDB IDs		2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Potassium Ion Export Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Heart Rate By Hormone Regulation Of Chromosome Organization Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Homeostatic Process Protection From Non-homologous End Joining At Telomere DNA Replication Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Nucleobase-containing Compound Metabolic Process Replicative Cell Aging Regulation Of Heart Rate By Chemical Signal Regulation Of Nuclear Cell Cycle DNA Replication Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Negative Regulation Of Telomerase Activity Peptidyl-histidine Phosphorylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Potassium Ion Export Regulation Of Telomere Maintenance Via Telomerase Cellular Nitrogen Compound Metabolic Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Positive Regulation Of Microtubule Polymerization Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Regulation Of Telomerase Activity Phosphorelay Signal Transduction System Response To Drug MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Potassium Ion Transmembrane Transport Nitrogen Compound Metabolic Process Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Negative Regulation Of Potassium Ion Transport
Tagcloud ?			arginine assembly associates catalytic complementation destabilizes hela hypophosphorylation immunodepletion integration knock predominantly prp28 ribonucleoprotein rnai rs serine snrnp spliceosomal spliceosome splicing srpk1 srpk2 tri u1 u4 u5 u6 viability
Tagcloud (Difference) ?			arginine assembly associates catalytic complementation destabilizes hela hypophosphorylation immunodepletion integration knock predominantly prp28 ribonucleoprotein rnai rs serine snrnp spliceosomal spliceosome splicing srpk1 srpk2 tri u1 u4 u5 u6 viability
Tagcloud (Intersection) ?