WBP4 and CHTF8

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	CHTF8
Gene Name		WW domain binding protein 4	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	DNA Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	6 interactors: AP4M1 DSCC1 EIF4EBP1 PCNA RFC3 WBP4
Entrez ID		11193	54921
HPRD ID		16086	16797
Ensembl ID		ENSG00000120688	ENSG00000168802
Uniprot IDs		B7Z4M2 O75554	P0CG13
PDB IDs		2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Cell Cycle Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening DNA Replication Transcription-coupled Nucleotide-excision Repair Cell Cycle Process Cell Cycle Telomere Maintenance Nucleotide-excision Repair Positive Regulation Of Deoxyribonuclease Activity DNA-dependent DNA Replication DNA Biosynthetic Process Regulation Of DNA Replication Mitotic Cell Cycle Process Leading Strand Elongation G1/S Transition Of Mitotic Cell Cycle Post-translational Protein Acetylation Maintenance Of Mitotic Sister Chromatid Cohesion IRES-dependent Translational Initiation Cap-independent Translational Initiation DNA Recombination Chromosome Organization DNA Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cytoplasmic Translational Initiation Translesion Synthesis Mitotic Sister Chromatid Cohesion Cytoplasmic Translation DNA Synthesis Involved In DNA Repair MRNA Cis Splicing, Via Spliceosome Golgi To Endosome Transport Negative Regulation Of Translational Initiation Postreplication Repair TOR Signaling Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Sister Chromatid Cohesion Response To Ischemia DNA Repair Cellular Homeostasis Positive Regulation Of Nuclease Activity Nucleobase-containing Compound Metabolic Process
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