WBP4 and SF3B3

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	SF3B3
Gene Name		WW domain binding protein 4	splicing factor 3b, subunit 3, 130kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	RNA Binding Protein Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Protein Complex Assembly RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	27 interactors: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		11193	23450
HPRD ID		16086	12027
Ensembl ID		ENSG00000120688
Uniprot IDs		B7Z4M2 O75554	A8K6V3 Q15393
PDB IDs		2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Process Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Respiratory Burst After Phagocytosis Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Cardiac Muscle Contraction Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Heart Contraction Positive Regulation Of Response To DNA Damage Stimulus Peptidyl-amino Acid Modification Threonylcarbamoyladenosine Biosynthetic Process Leukocyte Migration Involved In Immune Response Regulation Of Heart Rate By Hormone N-acetylmannosamine Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ossification Response To Growth Factor Positive Regulation Of Cell Death Actin Polymerization-dependent Cell Motility Striated Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway N-acetylneuraminate Catabolic Process
Tagcloud ?			advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Difference) ?			advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Intersection) ?