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WBP4 and SFPQ
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
WBP4
SFPQ
Gene Name
WW domain binding protein 4
splicing factor proline/glutamine-rich
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Plasma Membrane
Nuclear Speck
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Paraspeckles
Molecular Function
Nucleic Acid Binding
Protein Binding
Zinc Ion Binding
Proline-rich Region Binding
Nucleotide Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Core Promoter Binding
Protein Binding
Histone Deacetylase Binding
Transcription Regulatory Region DNA Binding
Poly(A) RNA Binding
Biological Process
MRNA Cis Splicing, Via Spliceosome
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Alternative MRNA Splicing, Via Spliceosome
DNA Repair
DNA Recombination
Transcription, DNA-templated
MRNA Processing
RNA Splicing
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Histone H3 Deacetylation
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Crohn's disease (
23266558
)
Endometrial cancer (
21499250
)
Protein-Protein Interactions
44 interactors:
BUB3
CAPRIN1
CHERP
CHTF8
CPSF6
CPSF7
DDX23
DDX3X
DHX15
DIAPH1
DNM2
EFTUD2
EWSR1
FUS
HLTF
HNRNPK
HNRNPU
HTATSF1
KHDRBS1
NONO
PABPC1
PRPF3
PRPF4
PRPF40A
PSPC1
SART1
SCAF4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B3
SF3B4
SFPQ
SNRNP70
SNRPA
SNRPB
TCERG1
WAS
WBP11
WIPF1
XRCC6
ZNF207
27 interactors:
APBB1
AR
CSNK2A1
ERG
EXOSC5
FHL2
FUS
GAS7
HIST3H3
HN1
NONO
PIN1
PPARG
PPP1CA
PRPF40A
PSPC1
PTBP1
RAC1
SIN3A
SMAD5
SNRPA
SREK1
TCERG1
TOP1
UBC
WBP4
ZMYM2
Entrez ID
11193
6421
HPRD ID
16086
07284
Ensembl ID
ENSG00000120688
ENSG00000116560
Uniprot IDs
B7Z4M2
O75554
P23246
Q86VG2
PDB IDs
2DK1
2JXW
Enriched GO Terms of Interacting Partners
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MRNA Processing
RNA Splicing
RNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
MRNA 3'-splice Site Recognition
Ribonucleoprotein Complex Biogenesis
Cellular Metabolic Process
Cellular Macromolecular Complex Assembly
Spliceosomal Complex Assembly
Cellular Component Assembly
MRNA Splice Site Selection
Cellular Process
Metabolic Process
MRNA 3'-end Processing
Transcription, DNA-templated
RNA Biosynthetic Process
RNA 3'-end Processing
Spliceosomal SnRNP Assembly
Posttranscriptional Regulation Of Gene Expression
Attachment Of Spindle Microtubules To Kinetochore
Rhythmic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of Translational Initiation
Macromolecule Biosynthetic Process
Positive Regulation Of Translation
Actin Polymerization Or Depolymerization
Negative Regulation Of Gene Expression
MRNA Cis Splicing, Via Spliceosome
Negative Regulation Of Biosynthetic Process
Regulation Of MRNA Processing
Regulation Of Circadian Rhythm
Regulation Of RNA Metabolic Process
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of MRNA Splicing, Via Spliceosome
MRNA Stabilization
Positive Regulation Of Gene Expression
MRNA Polyadenylation
Cellular Response To Osmotic Stress
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Rhythmic Process
Regulation Of Circadian Rhythm
RNA Splicing
MRNA Metabolic Process
Transcription, DNA-templated
MRNA Processing
RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of Gene Expression
Regulation Of Apoptotic Process
RNA Processing
Regulation Of Cell Death
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Metabolic Process
Circadian Rhythm
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Regulation Of Transcription, DNA-templated
Intracellular Receptor Signaling Pathway
Negative Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
DNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Cellular Component Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Cell Cycle Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Biosynthetic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cellular Biosynthetic Process
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