WBP4 and WIPF1

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	WIPF1
Gene Name		WW domain binding protein 4	WAS/WASL interacting protein family, member 1
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	Actin Binding Protein Binding Profilin Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	Protein Complex Assembly Actin Polymerization Or Depolymerization Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Response To Other Organism
Pathways			Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	22 interactors: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70
Entrez ID		11193	7456
HPRD ID		16086	03835
Ensembl ID		ENSG00000120688	ENSG00000115935
Uniprot IDs		B7Z4M2 O75554	O43516 Q2YDC4
PDB IDs		2DK1 2JXW	2A41
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	Immune Response-activating Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Locomotion Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Immune Response Phagocytosis Endocytosis Actin Filament Organization Regulation Of Cytoskeleton Organization Innate Immune Response Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Immune Response Axon Guidance Cell Motility Positive Regulation Of Immune System Process Positive Regulation Of Organelle Organization Actin Filament-based Process Regulation Of Actin Filament-based Process Neuron Projection Morphogenesis Neuron Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Vesicle-mediated Transport Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Organization Neuron Differentiation Axonogenesis Cell Projection Organization Cell Projection Morphogenesis Axon Development Cell Part Morphogenesis Actin Polymerization Or Depolymerization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Organelle Organization Immune System Process Immune Response
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