SF3A3 and ADAP1

Number of citations of the paper that reports this interaction (PMID 12565890)
3

Data Source:
HPRD (in vitro)

		SF3A3	ADAP1
Gene Name		splicing factor 3a, subunit 3, 60kDa	ArfGAP with dual PH domains 1
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	Cell Surface Receptor Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of GTPase Activity Positive Regulation Of GTPase Activity
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ADAP1 APBB1 APP CCDC85B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212	23 interactors: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		10946	11033
HPRD ID		10411	09733
Ensembl ID		ENSG00000183431	ENSG00000105963
Uniprot IDs		B3KY12 E7EUT8 Q12874	O75689
PDB IDs		2DT7	3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing RNA Splicing Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Visual Learning Visual Behavior Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA 3'-end Processing Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Synaptic Growth At Neuromuscular Junction Associative Learning Axon Guidance Collateral Sprouting In Absence Of Injury Histone Modification RNA 3'-end Processing Histone Acetylation Regulation Of Cell Cycle Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Tubulin Deacetylation MRNA 3'-splice Site Recognition Protein Acetylation Programmed Cell Death Learning Regulation Of Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Death Death Axon Choice Point Recognition Negative Regulation Of Cell Growth Axonogenesis Regulation Of Transcription From RNA Polymerase II Promoter	Peptidyl-serine Phosphorylation Intracellular Signal Transduction Intracellular Transport Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Phosphorylation Cellular Localization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Cell Adhesion Regulation Of Glucose Import Signaling Cellular Response To Fibroblast Growth Factor Stimulus Cell Communication Regulation Of Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Negative Regulation Of Glial Cell Apoptotic Process Anatomical Structure Morphogenesis Positive Regulation Of Phospholipase Activity
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