WBP4 and DHX15

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	DHX15
Gene Name		WW domain binding protein 4	DEAH (Asp-Glu-Ala-His) box helicase 15
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus Cytoplasm U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	RNA Helicase Activity Double-stranded RNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)	Myopia (pathological) ( 23049088)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	12 interactors: APBB1 DDX42 NKAP PIN1 PINX1 PRPF40A RBM17 TRA2A WBP4 YWHAB YWHAG ZGPAT
Entrez ID		11193	1665
HPRD ID		16086	04553
Ensembl ID		ENSG00000120688	ENSG00000109606
Uniprot IDs		B7Z4M2 O75554	O43143
PDB IDs		2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	RNA Splicing MRNA Processing Gene Expression Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway MRNA Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Cycle RNA Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Cytokinesis Negative Regulation Of Transferase Activity Nucleobase-containing Compound Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Mitochondrion Organization Regulation Of Protein Phosphorylation Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphorylation Positive Regulation Of Cell Death Intrinsic Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Phosphorus Metabolic Process Cellular Metabolic Process Cellular Response To Insulin Stimulus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Regulation Of Protein Kinase Activity Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Intracellular Transport Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process
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