WBP4 and ZNF207

Number of citations of the paper that reports this interaction (PubMedID 16055720)
76

Data Source:
BioGRID (pull down)

		WBP4	ZNF207
Description		WW domain binding protein 4	zinc finger protein 207
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Spindle Cytoskeleton Microtubule Spindle Matrix
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Proline-rich Region Binding	DNA Binding RNA Binding Protein Binding Microtubule Binding Heparin Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome	Mitotic Sister Chromatid Segregation Microtubule Bundle Formation Chromosome Segregation Mitotic Spindle Assembly Checkpoint Signaling Attachment Of Spindle Microtubules To Kinetochore Microtubule Polymerization Protein Stabilization Cell Division Regulation Of Chromosome Segregation Mitotic Spindle Assembly
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Survival in pancreatic cancer ( 28470677)
Interacting Genes		66 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 CSDE1 DDX23 DDX3X DHX15 DHX38 DIAPH1 DMRTB1 DNM2 EFTUD2 EIF4ENIF1 EIF5B EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 LARP4 NONO OGT PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 RARS1 RBM22 RBM42 RBPMS SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP27 SNRNP70 SNRPA SNRPB SNW1 SQSTM1 TCERG1 TFIP11 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207	10 interacting genes: CEBPA ERBB3 HNRNPM HNRNPUL1 MAP2K2 OGT POLR1B TET2 WBP4 WDR77
Entrez ID		11193	7756
HPRD ID		16086	04576
Ensembl ID		ENSG00000120688	ENSG00000010244
Uniprot IDs		O75554	O43670
PDB IDs		2DK1 2JXW 5O9Z 6AHD 7OS1 8H6K 8H6L 8Q7N 8QO9 8QPE 8QZS
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Spliceosomal Complex RNA Processing RNA Metabolic Process Nucleic Acid Binding Catalytic Step 2 Spliceosome Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm Nucleus Nuclear Speck U2-type Precatalytic Spliceosome Macromolecule Metabolic Process U4/U6 X U5 Tri-snRNP Complex MRNA Binding U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex Spliceosomal Complex Assembly Protein-RNA Complex Assembly Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Poly(A) Binding Protein-containing Complex Assembly Cellular Component Assembly Protein-containing Complex Organization Regulation Of MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex Regulation Of MRNA Processing Cytoplasmic Stress Granule MRNA 3'-splice Site Recognition MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome Membraneless Organelle Assembly Paraspeckles Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Translation Pre-mRNA Binding Nuclear Matrix U1 SnRNP U1 SnRNP Binding Positive Regulation Of Translation Protein Binding	ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Positive Regulation Of Gene Expression Schwann Cell Development Macromolecule Metabolic Process ERBB2 Signaling Pathway Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nucleoplasm RNA Splicing, Via Transesterification Reactions Cellular Developmental Process RNA Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Glial Cell Development Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Oocyte Axis Specification Positive Regulation Of Biosynthetic Process Chromatin DNA Binding CHOP-C/EBP Complex Positive Regulation Of RNA Biosynthetic Process Nucleus Cell Development Positive Regulation Of DNA-templated Transcription Response To Vitamin B2 Positive Regulation Of Macromolecule Biosynthetic Process C/EBP Complex Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB Signaling Pathway Myelination Axon Ensheathment MRNA Processing RNA Splicing Protein O-acetylglucosaminyltransferase Activity DNA 5-methylcytosine Dioxygenase Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Ribonucleoside Binding Nucleologenesis Protein O-linked Glycosylation Positive Regulation Of RNA Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Matrix White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development
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