WBP4 and EFTUD2

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WBP4	EFTUD2
Gene Name		WW domain binding protein 4	elongation factor Tu GTP binding domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck	Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	MRNA Cis Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	16 interactors: ARPC3 CYFIP1 GOLM1 GSK3B HINFP HSPB1 LSM8 PIN1 PRPF6 PRPF8 SF1 SF3B3 SF3B4 SNRNP40 SREK1 WBP4
Entrez ID		11193	9343
HPRD ID		16086	04869
Ensembl ID		ENSG00000120688	ENSG00000108883
Uniprot IDs		B7Z4M2 O75554	B3KX19 B4DMC0 K7EJ81 Q15029
PDB IDs		2DK1 2JXW
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress	RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Positive Regulation Of Cellular Metabolic Process Spliceosomal Complex Assembly Ribonucleoprotein Complex Biogenesis Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Phosphorylation Positive Regulation Of Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Gene Expression Regulation Of Organelle Organization Hypermethylation Of CpG Island Primary Sex Determination Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Cellular Biosynthetic Process MRNA 3'-splice Site Recognition Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Interleukin-3 Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Female Gonad Development Positive Regulation Of Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Axonogenesis Negative Regulation Of MAPK Cascade Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Microtubule Positive Regulation Of Actin Nucleation Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Protein Complex Assembly
Tagcloud ?			3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Difference) ?			3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Intersection) ?