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COPS8 and COPS6
Number of citations of the paper that reports this interaction (PMID
11337588
)
171
Data Source:
BioGRID
(biochemical, biochemical)
HPRD
(in vitro)
COPS8
COPS6
Gene Name
COP9 signalosome subunit 8
COP9 signalosome subunit 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Nucleoplasm
Cytoplasm
COP9 Signalosome
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Activation Of NF-kappaB-inducing Kinase Activity
Negative Regulation Of Cell Proliferation
Cullin Deneddylation
Cullin Deneddylation
Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
CUL1
CUL5
DDB1
EIF3E
GPS1
ITPK1
JUN
MAPRE1
NFKBIA
TP53
USHBP1
84 interactors:
ANXA1
ANXA7
BTBD2
C1orf174
C4orf17
CASP3
CASP6
CASP7
CASP8
CCDC106
CDH10
CDKN1A
CDKN2C
CHRNB1
COPS2
COPS3
COPS4
COPS5
COPS8
COX17
COX5A
CRELD1
CUL1
CUL5
DIS3L2
DLEU1
EDN1
EIF3E
EMD
EP300
ERH
FAU
GPS1
HMOX2
JUN
LAMA4
LPL
MAP7D1
MAPK6
MAPKAPK3
MIF
MNAT1
MYCBP
NEDD8
NR3C1
ORAI2
PAEP
PAFAH1B3
PBX2
PDZK1IP1
PFKL
PHYHIP
PMF1
PRKRA
PSAP
PSMD11
PTEN
QTRT1
RAB27A
RBX1
RFC5
ROGDI
RPA2
RPL15
S100A10
SAT1
SERPINA5
SERPINB9
SLC2A1
SMN1
SNRPG
STK40
STX5
SULT1E1
TDGF1
TK1
TP53
TP63
TRDMT1
TRIB3
VIM
WIPI2
ZEB2
ZNF24
Entrez ID
10920
10980
HPRD ID
16737
16735
Ensembl ID
ENSG00000168090
Uniprot IDs
Q99627
Q7L5N1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cullin Deneddylation
Protein Deneddylation
Protein Modification By Small Protein Removal
Viral Process
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Response To Abiotic Stimulus
Protein Import Into Nucleus
Apoptotic Signaling Pathway
Nuclear Import
Cell Proliferation
Cell Cycle Arrest
Protein Metabolic Process
Protein Import
Protein Import Into Nucleus, Translocation
Release Of Cytochrome C From Mitochondria
Cellular Macromolecule Catabolic Process
Protein Localization To Nucleus
Response To Radiation
Circadian Rhythm
Interaction With Symbiont
Intrinsic Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Protein Localization To Organelle
Modification-dependent Protein Catabolic Process
Apoptotic Process
Protein Monoubiquitination
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cell Death
Negative Regulation Of DNA Binding
Death
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Protein Catabolic Process
Toll-like Receptor 10 Signaling Pathway
Regulation Of Binding
Mitotic Cell Cycle Phase Transition
Nucleocytoplasmic Transport
Cell Cycle Phase Transition
Nuclear Transport
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Cellular Response To UV
Cellular Response To Potassium Ion Starvation
Positive Regulation Of Neuron Apoptotic Process
Toll-like Receptor 2 Signaling Pathway
Cullin Deneddylation
Protein Deneddylation
Developmental Process
Intrinsic Apoptotic Signaling Pathway
Cellular Metabolic Process
Anatomical Structure Development
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Regulation Of Catalytic Activity
Tissue Development
Mitotic Cell Cycle
Programmed Cell Death
Apoptotic Signaling Pathway
Response To Stress
Cell Death
Catabolic Process
Death
Regulation Of Cell Proliferation
Mitotic Cell Cycle Process
Cellular Response To Stress
Response To Abiotic Stimulus
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Apoptotic Process
Regulation Of Phosphorylation
Response To Organic Cyclic Compound
Cell Cycle
Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cellular Metabolic Process
Cell Cycle Phase Transition
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Cycle
Organ Development
Multicellular Organismal Development
Epithelium Development
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Cell Death
Response To Stimulus
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
System Development
Negative Regulation Of Cell Death
Cellular Macromolecule Catabolic Process
Response To Organic Substance
Regulation Of Protein Kinase Activity
Positive Regulation Of Cell Death
Tagcloud
?
aiming
aip
alignment
boar
brms1
chordc1
clues
csde1
csfv
ddx5
domestic
fever
gnb2l1
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Difference)
?
aiming
aip
alignment
boar
brms1
chordc1
clues
csde1
csfv
ddx5
domestic
fever
gnb2l1
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Intersection)
?