COPS6 and PAEP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPS6	PAEP
Gene Name		COP9 signalosome subunit 6	progestagen-associated endometrial protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome	Extracellular Region
	Molecular Function	Protein Binding	Small Molecule Binding
	Biological Process	Cullin Deneddylation Viral Process	Transport Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24	11 interactors: A2M APP COPS6 EEF1A1 GRAMD3 IGSF21 LRIF1 PTPRC SMAD3 UBE2E1 XRCC6
Entrez ID		10980	5047
HPRD ID		16735	01411
Ensembl ID		ENSG00000168090	ENSG00000122133
Uniprot IDs		Q7L5N1	P09466
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death	Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Cell Activation Negative Regulation Of Catalytic Activity Positive Regulation Of Proteolysis Regulation Of Humoral Immune Response Regulation Of Cell Cycle Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Platelet Degranulation Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Response To Radiation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Immunoglobulin Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hematopoietic Stem Cell Migration Negative Regulation Of Complement Activation, Lectin Pathway Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Viral Process Negative Regulation Of Immune Response Cellular Hyperosmotic Salinity Response Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Wound Healing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Peptidase Activity Response To Ionizing Radiation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Catalytic Activity Regulation Of Cell Differentiation Regulation Of Extracellular Matrix Assembly Collateral Sprouting Axon Midline Choice Point Recognition Immune System Development Response To Wounding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	acaca crh deregressed dgat1 fasn fertility fp fy gh1 holstein lep lgb longevity mastitis mfge8 milk mscc pft piebaldism positives pp ppargc1a proofs py relatedness sires thrsp tph1 traits
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	acaca crh deregressed dgat1 fasn fertility fp fy gh1 holstein lep lgb longevity mastitis mfge8 milk mscc pft piebaldism positives pp ppargc1a proofs py relatedness sires thrsp tph1 traits
Tagcloud (Intersection) ?